NEDD8 anticorps
(1 reference)Aperçu rapide pour NEDD8 anticorps (ABIN969546)
Antigène
Voir toutes NEDD8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- NEDD8 Antibody
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Purification
- Purified antibody
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Immunogène
- Purified recombinant fragment of human NEDD8 expressed in E. Coli.
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Isotype
- IgG1
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anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) antibody
NEDD8 Reactivité: Humain WB, IHC, ELISA, ICC, FACS Hôte: Souris Monoclonal 5B8 unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) antibodyNEDD8 Reactivité: Humain, Souris, Rat, Singe WB, IHC, ELISA, IF, ICC Hôte: Lapin Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) (N-Term) antibodyNEDD8 Reactivité: Humain, Souris, Rat, Singe, Boeuf (Vache), Xenopus laevis WB, IHC, IF, IHC (p), IP, FACS Hôte: Lapin Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) antibodyNEDD8 Reactivité: Humain WB, IF, IHC (p), FACS, EIA Hôte: Souris Monoclonal 1A7 unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) (AA 1-81) antibodyNEDD8 Reactivité: Humain WB, IHC, ELISA, IF Hôte: Lapin Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) (N-Term) antibodyNEDD8 Reactivité: Humain, Souris, Rat, Singe WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) (AA 1-32), (N-Term) antibodyNEDD8 Reactivité: Humain WB, IHC (p) Hôte: Lapin Polyclonal RB0639 unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) (AA 1-32) antibodyNEDD8 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) (N-Term) antibodyNEDD8 Reactivité: Humain WB, IHC, ELISA Hôte: Lapin Polyclonal unconjugated
anti-Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) antibodyNEDD8 Reactivité: Humain WB, IHC, ELISA, IF, IHC (p), FACS Hôte: Souris Monoclonal 5B8 unconjugated
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Indications d'application
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "The mechanism of poly-NEDD8 chain formation in vitro." dans: Biochemical and biophysical research communications, Vol. 381, Issue 3, pp. 443-7, (2009) (PubMed).
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: "The mechanism of poly-NEDD8 chain formation in vitro." dans: Biochemical and biophysical research communications, Vol. 381, Issue 3, pp. 443-7, (2009) (PubMed).
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- NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
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Autre désignation
- NEDD8
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Sujet
- Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.Tissue specificity: Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.
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Poids moléculaire
- 9 kDa
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ID gène
- 4738
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UniProt
- Q15843
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Pathways
- Ubiquitin Proteasome Pathway
Antigène
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