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Les anticorps anti-SARS-CoV-2

La protéine Spike du SARS-CoV-2 demeure la cible essentielle pour les vaccins, les anticorps thérapeutiques et les tests sérologiques, mais l’évolution continue du virus a introduit des mutations — en particulier dans le RBD — pouvant modifier la liaison des anticorps et réduire leur capacité de neutralisation. Comme les variants circulants s’éloignent de la protéine Spike d’origine, les réactifs de première génération ne suffisent plus, rendant indispensables des anticorps mis à jour ou à large neutralisation pour une recherche et un développement fiables. Découvrez ci-dessous la sélection d’anticorps Spike SARS-CoV-2 de haute qualité proposée par antibodies-online !

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Recombinant SARS-CoV-2 Spike S1 anticorps (RBD)

Reactivité: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV), SARS CoV-2 Alpha, SARS CoV-2 Beta, SARS CoV-2 Epsilon, SARS CoV-2 Gamma, SARS CoV-2 Eta, SARS CoV-2 Kappa, SARS CoV-2 Delta, SARS CoV-2 Omicron ELISA, IF, Crys, SPR Hôte: Human Monoclonal CR3022 unconjugated Recombinant Antibody

Multiplex Immunohistochemistry validation image for anti-SARS-CoV-2 Spike S1 (RBD) antibody (ABIN6952546)

Multiplex Immunohistochemistry validation image for anti-SARS-CoV-2 Spike S1 (RBD) antibody (ABIN6952546)

Binding curve of four different formats of anti-COVID-19 & SARS-CoV S glycoprotein antibody CR3022 (ABIN6952546) to SARS-CoV-2 Spike Glycoprotein domains S1 and S2 (His-Tag (Insect Cells)).

Binding curve of anti-COVID-19 & SARS-CoV S glycoprotein antibody CR3022 (ABIN6952546) to SARS-CoV-2 Spike Glycoprotein domains S1 and S2 of various origin.

Binding curve of anti-COVID-19 & SARS-CoV S glycoprotein antibody CR3022 (ABIN6952546) to SARS-CoV-2 Spike Glycoprotein (S1), Sheep Fc-Tag and SARS-CoV-2 Spike Glycoprotein (S2), Sheep Fc-Tag from HEK293 cells.

Binding curve of anti-COVID-19 & SARS-CoV S glycoprotein antibody CR3022 to SARS-CoV-2 Spike Glycoprotein domains S1 and S2 (His-Tag (Insect Cells)).

Biolayer interferometry was used to determine dissociation constants of SARS-BLOCK™ peptides associated with IgG neutralizing antibody (ABIN6952546).

Microscale thermophoresis measurement of binding of anti-SARS-CoV-2 Spike S1 antibody (RBD) CR3022 (ABIN6952546) to SARS-CoV-2 Spike (Trimer) protein (ABIN6952670).

Microscale thermophoresis measurement of binding of anti-SARS-CoV-2 Spike S1 antibody (RBD) CR3022 (ABIN6952546) to SARS-CoV-2 Spike (B.

Microscale thermophoresis measurement of binding of anti-SARS-CoV-2 Spike S1 antibody (RBD) CR3022 (ABIN6952546) to SARS-CoV-2 Spike (B.

Microscale thermophoresis measurement of binding of anti-SARS-CoV-2 Spike S1 antibody (RBD) CR3022 (ABIN6952546) to SARS-CoV-2 Spike (P.

Surface expression and recognition of minispike by COVID-19 patient serum.

VeroE6 cells infected over night with VSVDeltaG-minispike-eGFP (green) are recognized by IgG of S ELISA-positive patients in contrast to a control replicon expressing blue fluorescent protein (VSVDeltaG-BFP).

Microscale thermophoresis measurement of binding of anti-SARS-CoV-2 Spike S1 antibody (RBD) CR3022 (ABIN6952546) to SARS-CoV-2 Spike (B.

Microscale thermophoresis measurement of binding of anti-SARS-CoV-2 Spike S1 antibody (RBD) CR3022 (ABIN6952546) to SARS-CoV-2 Spike (B.

Mutations (indicated in orange) in the SARS-CoV-2 S Protein Receptor Binding Domain (RBD) in variants of concern (grey) and variants of note (mint).

Microscale thermophoresis measurement of binding of anti-SARS-CoV-2 Spike S1 antibody (RBD) CR3022 (ABIN6952546) to SARS-CoV-2 Spike (B.

17 images

8 références

Independent Validation

1 validation

N° du produit ABIN6952546

Independently Validated

SARS-CoV-2 Spike anticorps (C-Term)

Reactivité: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV) ELISA, WB, IF, IHC Hôte: Lapin Polyclonal unconjugated

ELISA Test Antibodies: SARS-CoV-2 (COVID-19, 2019-nCoV) Spike antibody, ABIN1030641 (1 μg/mL).

Immunofluorescence Validation of SARS-CoV-2 (COVID-19) Spike in 293T Cells.

Immunohistochemical analysis of paraffin-embedded COVID-19 patient lung tissue using anti-SARS-CoV-2 (COVID-19) Spike S2 antibody (ABIN1030641, 0.

Immunohistochemical analysis of paraffin-embedded COVID-19 patient lung tissue using anti-SARS-CoV-2 (COVID-19) Spike S2 antibody (ABIN1030641, 0.

IHC/IF Validation in COVID-19 Patient Sample (Source: Nuovo et al.

IF Validation of SARS-CoV2 Spike in COVID-19 Patient Lung (Source: Magro et al.

IF Validation of SARS-CoV2 Spike in COVID-19 Patient Skin (Source: Magro et al.

IHC Validation of SARS-CoV2 Spike in the Nasopharyngeal Swab Sample of the COVID-19 Patient.

IHC Validation of SARS-CoV2 Spike in COVID-19 Patient Lung.

IHC Validation of SARS-CoV2 Spike in COVID-19 Patient Brain.

Overexpression Validation in Spike Transfected 293 Cells.

11 images

9 références

N° du produit ABIN1030641

SARS-CoV-2 Spike anticorps

Reactivité: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Beta, SARS CoV-2 Gamma, SARS CoV-2 Alpha ELISA, WB Hôte: Lapin Polyclonal unconjugated

Direct ELISA of SARS-CoV-2 variant proteins with anti-SARS-CoV-2 Spike S1 antibody ABIN6952962.

Immunofluorescence Validation of SARS-CoV-2 (COVID-19) Spike (cleavage site) in 293 Transfected CellsImmunofluorescent analysis of 4 % paraformaldehyde-fixed Spike transfected 293cells labeling SARS-CoV-2 (COVID-19) Spike (cleavage site) with ABIN6952962 at 10 mg/mL, followed by goat anti-rabbit IgG secondary antibody at 1/500 dilution (green) and DAPI staining (blue).

Overexpression Validation in Spike Transfected 293 Cells Loading: 10 μg per lane of 293 cell lysate.

Western Blot Validation with SARS-CoV-2 (COVID-19) Spike S1 Recombinant Protein Loading: 50 ng per lane of SARS-CoV-2 (COVID-19) Spike S1 recombinant protein (97-087).

ELISA Validation with SARS-CoV-2 (COVID-19) Spike S1 Recombinant ProteinAntibodies: SARS-CoV-2 (COVID-19) Spike antibody (cleavage site), ABIN6952962 (1 μg/mL).

Western Blot Validation with SARS-CoV-2 (COVID-19) Spike Recombinant Protein Loading: 30 ng per lane of SARS-CoV-2 (COVID-19) Spike RBD+SD1+SD2 recombinant protein, 10-305.

ELISA Validation with SARS-CoV-2 (COVID-19) Spike Recombinant ProteinAntibodies: SARS-CoV-2 (COVID-19) Spike antibody (cleavage site), ABIN6952962.

ELISA Validation of SARS-CoV-2 Spike Antibody Pair A sandwich ELISA was performed using the anti-SARS-COV-2 Spike S1 antibodies ABIN6952962 (10 μg/mL ) as the capture antibody.

8 images

N° du produit ABIN6952962

Recombinant SARS-CoV-2 Spike anticorps (AA 319-541)

Animal-Free Reactivité: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB, FACS, IF Hôte: Souris Monoclonal AB68-A09 unconjugated Recombinant Antibody

S1 Protein of different beta-corona strains were coated on an ELISA plate at 100 ng.

Calu-3 cells were infected with SARS-CoV-2 (B.

S1 Protein of different corona strain mutants (produced in Hi5 cells) were coated on an ELISA plate at 100 ng.

Sandwich ELISA assay with S1 protein of SARS-Cov-2.

4 images

N° du produit ABIN7581775

Recombinant SARS-CoV-2 Spike S1 anticorps (RBD)

Reactivité: SARS Coronavirus-2 (SARS-CoV-2), SARS Coronavirus (SARS-CoV), SARS CoV-2 Alpha, SARS CoV-2 Beta, SARS CoV-2 Epsilon, SARS CoV-2 Gamma, SARS CoV-2 Eta, SARS CoV-2 Kappa ELISA, IF, Crys, SPR Hôte: Lapin Chimeric CR3022 unconjugated Recombinant Antibody

Binding curve of anti-COVID-19 & SARS-CoV S glycoprotein antibody CR3022 (ABIN6952546) to SARS-CoV-2 Spike Glycoprotein domains S1 and S2 of various origin.

Mutations (indicated in red) in the SARS-CoV-2 S Protein receptor binding domain (RBD, mint) in variants of concern (light grey) and variants of note (light mint).

Binding curve of anti-COVID-19 & SARS-CoV S glycoprotein antibody CR3022 (ABIN6952546) to SARS-CoV-2 Spike Glycoprotein (S1), Sheep Fc-Tag and SARS-CoV-2 Spike Glycoprotein (S2), Sheep Fc-Tag from HEK293 cells.

3 images

5 références

N° du produit ABIN6952547

Recombinant SARS-CoV-2 Spike S1 anticorps (RBD)

Reactivité: SARS Coronavirus-2 (SARS-CoV-2) ELISA, GICA, Neut Hôte: Human Monoclonal A1 unconjugated single-domain Antibody (sdAb) Recombinant Antibody

The Binding Activity of SARS-CoV-2 Spike RBD Nanobody with SARS-CoV-2-S1-RBD.

GICA: In the Colloidal Gold Immunochromatography Assay detection system, the background of antibody (ABIN6953152) is clean, the detection limit can be as low as 25 ng/mL (1.

Activity: Binding signal of SARS-CoV-2 Spike RBD Nanobody (ABIN6953152) and SARS-CoV-2-S1-RBD (ABIN6953166) was inhibited by ACE2 protein-HRP conjugated inhibitor with the IC50 is 1.

Neutralizing Assay: Binding signal of SARS-CoV-2 Spike RBD Nanobody (ABIN6953152) and SARS-CoV-2-S1-RBD (ABIN6953166) was inhibited by ACE2 protein-HRP conjugated inhibitor with the IC50 is 0.

4 images

N° du produit ABIN6953152

SARS-CoV-2 Spike S1 anticorps

Reactivité: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Alpha, SARS CoV-2 Beta, SARS CoV-2 Epsilon, SARS CoV-2 Gamma ELISA, Neut Hôte: Human Chimeric AM122 unconjugated

Immobilized Human ACE2, His Tag (ABIN6952641) at 2 μg/mL (100 μL/well) can bind pre-mixed increasing concentrations of Anti-SARS-CoV-2 Neutralizing Antibody, Mouse IgG1 (ABIN6953206) and 0.

Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (ABIN6953206) on SDS-PAGE under reducing (R) and non-reducing (NR) conditions.

The purity of Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM122) (ABIN6953206) was more than 90% and the molecular weight of this protein is around 135-150 kDa verified by SEC-MALS.

Immobilized SARS-CoV-2 S1 protein, His Tag (ABIN6973257) at 2 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Spike RBD Antibody, Chimeric mAb, Human IgG1 (AM122) (ABIN6953206) with a linear range of 0.

Immobilized Anti-SARS-CoV-2 Spike S1 Antibody, chimeric mAb (ABIN6953206) at 2 μg/mL (100 μL/well) can bind S protein RBD.

5 images

N° du produit ABIN6953206

Recombinant SARS-CoV-2 Spike anticorps

Reactivité: SARS Coronavirus-2 (SARS-CoV-2) ELISA, WB Hôte: Human Monoclonal AM004414 (414-4) unconjugated Recombinant Antibody

SARS-CoV-2 Spike Antibody (clone AM004414) tested by ELISA.

SARS-CoV-2 Spike Antibody (AM004414) tested by Western blot.

2 images

N° du produit ABIN6972668

Recombinant SARS-CoV-2 Spike anticorps

Reactivité: SARS Coronavirus-2 (SARS-CoV-2) ELISA Hôte: Human Monoclonal AM015553 (553-15) unconjugated Recombinant Antibody

AbFlex SARS-CoV-2 Spike Antibody (rAb) (AM015553) tested by ELISA using SARS Spike protein ECD.

AbFlex SARS-CoV-2 Spike Antibody (rAb) (AM015553) tested by ELISA using SARS Spike protein RBD.

2 images

N° du produit ABIN6972674

Recombinant SARS-CoV-2 Spike anticorps (AA 319-541)

Reactivité: SARS Coronavirus-2 (SARS-CoV-2) ELISA, FACS Hôte: Lapin Monoclonal DM54 unconjugated Recombinant Antibody

Elisa plate pre-coated by 2 μg/mL (100 μL/well) SARS-CoV-2 RBD protein can bind Rabbit Anti-SARS-CoV-2 RBD monoclonal antibody (clone:DM54) in a linear range of 0.

Competition flow cytometry assay demonstrating Rabbit anti-RBD monoclonal antibody (clone: DM54) blockade of SARS-CoV-2 (COVID-19) S protein RBD (1 μg/mL, ABIN6961175, ABIN7042379 and ABIN7042380) binding to Expi 293 cell line transfected with human .

2 images

N° du produit ABIN6964062

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