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BCAR3 Produits

(Breast Cancer Anti-Estrogen Resistance 3 (BCAR3))

Catégories

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012].

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Catégories BCAR3 en vedette

BCAR3 Anticorps

High quality antibodies with extensive validation data.

BCAR3 Kits ELISA

Reliable ELISA kits for a wide range of species.

BCAR3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BCAR3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6260215
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, IF, ICC
Validations
  • (3)
N° du produit ABIN6257959
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN563616
Quantité 100 μg
Fiche technique Fiche technique

BCAR3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965237
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954192
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5648159
Quantité 96 tests
Fiche technique Fiche technique

BCAR3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346502
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3089928
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3130609
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits BCAR3

Sun, Cheng, Chen, Lim, Pallen: "Protein tyrosine phosphatase α phosphotyrosyl-789 binds BCAR3 to position Cas for activation at integrin-mediated focal adhesions." dans: Molecular and cellular biology, Vol. 32, Issue 18, pp. 3776-89, (2012) (PubMed).

Schrecengost, Riggins, Thomas, Guerrero, Bouton: "Breast cancer antiestrogen resistance-3 expression regulates breast cancer cell migration through promotion of p130Cas membrane localization and membrane ruffling." dans: Cancer research, Vol. 67, Issue 13, pp. 6174-82, (2007) (PubMed).

van Agthoven, van Agthoven, Dekker, van der Spek, Vreede, Dorssers: "Identification of BCAR3 by a random search for genes involved in antiestrogen resistance of human breast cancer cells." dans: The EMBO journal, Vol. 17, Issue 10, pp. 2799-808, (1998) (PubMed).

Synonymes et noms alternatifs relatifs à BCAR3

breast cancer anti-estrogen resistance 3 (BCAR3), breast cancer anti-estrogen resistance 3 (Bcar3), breast cancer anti-estrogen resistance 3 (bcar3), breast cancer anti-estrogen resistance 3 L homeolog (bcar3.L), AI131758, AND-34, BCAR3, NSP2, SH2D3B

Protein level used designations for BCAR3

  • SH2 domain-containing protein 3B
  • breast cancer anti-estrogen resistance protein 3
  • breast cancer antiestrogen resistance 3 protein
  • dJ1033H22.2 (breast cancer anti-estrogen resistance 3)
  • novel SH2-containing protein 2
  • p130Cas-binding protein AND-34
  • breast cancer anti-estrogen resistance 3
  • breast cancer antiestrogen resistance 3
  • breast cancer anti-estrogen resistance protein 3-like
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