BCL2A1 Produits
(BCL2-Related Protein A1 (BCL2A1))
Catégories
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories BCL2A1 en vedette
BCL2A1 Anticorps
High quality antibodies with extensive validation data.
BCL2A1 Kits ELISA
Reliable ELISA kits for a wide range of species.
BCL2A1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BCL2A1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (p)
Validations
- (1)
- (2)
N° du produit
ABIN388092
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
N° du produit
ABIN650621
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
N° du produit
ABIN7145318
Quantité
100 μg
Fiche technique
Fiche technique
BCL2A1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6975492
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954065
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Validations
N° du produit
ABIN1123380
Quantité
96 tests
Fiche technique
Fiche technique
BCL2A1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7121988
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1346548
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1346550
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits BCL2A1
: "Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways." dans: Oncotarget, Vol. 7, Issue 45, pp. 73080-73100, (2016) (PubMed).: "Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-kappaB-dependent pathways." dans: Journal of hepatology, Vol. 51, Issue 1, pp. 139-48, (2009) (PubMed).
: "Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity." dans: Occupational and environmental medicine, Vol. 66, Issue 12, pp. 848-53, (2009) (PubMed).
: "Mitogen-activated protein kinase inhibition induces translocation of Bmf to promote apoptosis in melanoma." dans: Cancer research, Vol. 69, Issue 5, pp. 1985-94, (2009) (PubMed).
: "Sirolimus-eluting versus bare-metal low-profile stent for renal artery treatment (GREAT Trial): angiographic follow-up after 6 months and clinical outcome up to 2 years." dans: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists, Vol. 14, Issue 4, pp. 460-8, (2007) (PubMed).
: "Weight loss reduces adipose tissue cathepsin S and its circulating levels in morbidly obese women." dans: The Journal of clinical endocrinology and metabolism, Vol. 91, Issue 3, pp. 1042-7, (2006) (PubMed).
: "Gene expression changes and signaling events associated with the direct antimelanoma effect of IFN-gamma." dans: Cancer research, Vol. 65, Issue 19, pp. 8869-77, (2005) (PubMed).
: "Up-regulation of Bfl-1/A1 via NF-kappaB activation in cisplatin-resistant human bladder cancer cell line." dans: Cancer letters, Vol. 212, Issue 1, pp. 61-70, (2004) (PubMed).
: "Cell death in the third millennium." dans: Cell death and differentiation, Vol. 7, Issue 1, pp. 2-7, (2000) (PubMed).
: "Structural basis of BFL-1 for its interaction with BAX and its anti-apoptotic action in mammalian and yeast cells." dans: The Journal of biological chemistry, Vol. 275, Issue 15, pp. 11092-9, (2000) (PubMed).
Synonymes et noms alternatifs relatifs à BCL2A1
BCL2 related protein A1 (BCL2A1), BCL2-related protein A1 (Bcl2a1), BCL2-related protein A1 (BCL2A1), ACC-1, ACC-2, BCL2A1, Bcl2a1d, BCL2L5, BFL1, GRS, HBPA1Protein level used designations for BCL2A1
- bcl-2-like protein 5
- bcl-2-related protein A1
- bcl2-L-5
- hematopoietic BCL2-related protein A1
- hemopoietic-specific early response protein
- protein BFL-1
- B-cell leukemia/lymphoma 2 related protein A1
- B-cell leukemia/lymphoma 2 related protein A1d
- BCL2-related protein A1d
- protein A1
- Bcl-2-like protein 5
- BCL2-related protein A1
- Bcl-2-related protein A1
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