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BCL6 Produits

(B-Cell CLL/lymphoma 6 (BCL6))

Catégories

The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of START-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Sep 2008].

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Catégories BCL6 en vedette

BCL6 Anticorps

High quality antibodies with extensive validation data.

BCL6 Kits ELISA

Reliable ELISA kits for a wide range of species.

BCL6 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BCL6 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (5)
N° du produit ABIN3187827
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (2)
  • (4)
N° du produit ABIN749843
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, FACS, IHC, ICC, Neut
Validations
  • (5)
N° du produit ABIN5611253
Quantité 0.1 mg
Fiche technique Fiche technique

BCL6 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965111
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380950
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6951387
Quantité 96 tests
Fiche technique Fiche technique

BCL6 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7121962
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346576
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3089985
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits BCL6

Huang, Zhang, Hou, Wang, Liu, Zhang, Chen, Zhu: "LncRNA AK023391 promotes tumorigenesis and invasion of gastric cancer through activation of the PI3K/Akt signaling pathway." dans: Journal of experimental & clinical cancer research : CR, Vol. 36, Issue 1, pp. 194, (2018) (PubMed).

Szabó, Gáspár, Dajnoki, Papp, Fábos, Szegedi, Zeher: "Expansion of circulating follicular T helper cells associates with disease severity in childhood atopic dermatitis." dans: Immunology letters, Vol. 189, pp. 101-108, (2017) (PubMed).

Gong, Zhu, Pang, Ai, Gong, La, Ding: "Increased levels of CCR7(lo)PD-1(hi) CXCR5+ CD4+ T cells, and associated factors Bcl-6, CXCR5, IL-21 and IL-6 contribute to repeated implantation failure." dans: Experimental and therapeutic medicine, Vol. 14, Issue 6, pp. 5931-5941, (2017) (PubMed).

Baumjohann, Okada, Ansel: "Cutting Edge: Distinct waves of BCL6 expression during T follicular helper cell development." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 187, Issue 5, pp. 2089-92, (2011) (PubMed).

Choi, Kageyama, Eto, Escobar, Johnston, Monticelli, Lao, Crotty: "ICOS receptor instructs T follicular helper cell versus effector cell differentiation via induction of the transcriptional repressor Bcl6." dans: Immunity, Vol. 34, Issue 6, pp. 932-46, (2011) (PubMed).

Crotty: "Follicular helper CD4 T cells (TFH)." dans: Annual review of immunology, Vol. 29, pp. 621-63, (2011) (PubMed).

Crotty, Johnston, Schoenberger: "Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation." dans: Nature immunology, Vol. 11, Issue 2, pp. 114-20, (2010) (PubMed).

Fazilleau, McHeyzer-Williams, Rosen, McHeyzer-Williams: "The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding." dans: Nature immunology, Vol. 10, Issue 4, pp. 375-84, (2009) (PubMed).

Nurieva, Chung, Martinez, Yang, Tanaka, Matskevitch, Wang, Dong: "Bcl6 mediates the development of T follicular helper cells." dans: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1001-5, (2009) (PubMed).

Johnston, Poholek, DiToro, Yusuf, Eto, Barnett, Dent, Craft, Crotty: "Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation." dans: Science (New York, N.Y.), Vol. 325, Issue 5943, pp. 1006-10, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à BCL6

B-cell CLL/lymphoma 6 L homeolog (bcl6.L), B-cell CLL/lymphoma 6 (bcl6), B-cell CLL/lymphoma 6 (BCL6), B cell leukemia/lymphoma 6 (Bcl6), B-cell CLL/lymphoma 6 (Bcl6), bcl5, Bcl5, BCL5, bcl6a, BCL6A, laz3, LAZ3, MGC132260, zbtb27, ZBTB27, znf51, ZNF51

Protein level used designations for BCL6

  • B-cell CLL/lymphoma 6
  • B-cell CLL/lymphoma 6 (zinc finger protein 51)
  • B-cell lymphoma 6 protein
  • zinc finger protein 51
  • B-cell leukemia/lymphoma 5
  • B-cell leukemia/lymphoma 6
  • B-cell lymphoma 6 protein homolog
  • B-cell lymphoma 5 protein
  • B-cell lymphoma 6 protein transcript
  • BCL-5
  • BCL-6
  • cys-his2 zinc finger transcription factor
  • lymphoma-associated zinc finger gene on chromosome 3
  • protein LAZ-3
  • zinc finger and BTB domain-containing protein 27
  • zinc finger transcription factor BCL6S
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