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BCR Protéines

(Breakpoint Cluster Region (BCR))

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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BCR Protein (AA 1-1270) (His tag)

custom-made BCR Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Mouse Recombinant Bcr Protein, UniprotID Q6PAJ1

3 images

N° du produit ABIN7564104

Détails

BCR Protein (AA 1-1271) (His tag)

custom-made BCR Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)

AlphaFold protein structure predicition of Human Recombinant BCR Protein, UniprotID P11274

3 images

N° du produit ABIN7552612

Détails

BCR Protein (AA 618-824) (His tag)

BCR Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.

N° du produit ABIN7505420

Détails

BCR Protein (AA 1042-1243) (His tag)

BCR Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC

N° du produit ABIN7418029

Détails

BCR Protein (AA 1042-1268) (His tag)

BCR Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC

N° du produit ABIN7419664

Détails

BCR Protein (His tag)

BCR Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % Inactive

N° du produit ABIN7668257

Détails

BCR Protein (AA 1-1270) (Strep Tag)

custom-made BCR Origine: Souris Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

N° du produit ABIN3135773

Détails

BCR Protein (AA 1-1271) (Strep Tag)

custom-made BCR Origine: Humain Hôte: Cell-free protein synthesis (CFPS) Recombinant approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC). WB, SDS, ELISA

N° du produit ABIN3089847