Beclin-1 participates in the regulation of autophagy and has an important role in development, tumorigenesis, and neurodegeneration (Zhong et al., 2009 [PubMed 19270693]).[supplied by OMIM, Jul 2010].
custom-made
BECN1
Origine: Souris
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
BECN1
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
custom-made
BECN1
Origine: Souris
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
custom-made
BECN1
Origine: Humain
Hôte: Cell-free protein synthesis (CFPS)
Recombinant
approximately 70-80 % as determined by SDS PAGE, Western Blot and analytical SEC (HPLC).
WB, SDS, ELISA
Dernières publications pour nos Beclin 1 Protéines
Zhu, Messer, Wang, Lin, Cham, Chang, Billiar, Lotze, Boone, Chang: "Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation." dans: The Journal of clinical investigation, Vol. 125, Issue 3, pp. 1098-110, (2015) (PubMed).
Giatromanolaki, Koukourakis, Koutsopoulos, Chloropoulou, Liberis, Sivridis: "High Beclin 1 expression defines a poor prognosis in endometrial adenocarcinomas." dans: Gynecologic oncology, Vol. 123, Issue 1, pp. 147-51, (2011) (PubMed).
Rohn, Wirawan, Brown, Harris, Masliah, Vandenabeele: "Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain." dans: Neurobiology of disease, Vol. 43, Issue 1, pp. 68-78, (2011) (PubMed).
Novgorodov, Chudakova, Wheeler, Bielawski, Kindy, Obeid, Gudz: "Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis." dans: The Journal of biological chemistry, Vol. 286, Issue 6, pp. 4644-58, (2011) (PubMed).