Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

Bestrophin 1 Produits

(Bestrophin 1 (BEST1))

Catégories

This gene encodes a member of the bestrophin gene family. This small gene family is characterized by proteins with a highly conserved N-terminus with four to six transmembrane domains. Bestrophins may form chloride ion channels or may regulate voltage-gated L-type calcium-ion channels. Bestrophins are generally believed to form calcium-activated chloride-ion channels in epithelial cells but they have also been shown to be highly permeable to bicarbonate ion transport in retinal tissue. Mutations in this gene are responsible for juvenile-onset vitelliform macular dystrophy (VMD2), also known as Best macular dystrophy, in addition to adult-onset vitelliform macular dystrophy (AVMD) and other retinopathies. Alternative splicing results in multiple variants encoding distinct isoforms.[provided by RefSeq, Nov 2008].

antibodies-online.com est synonyme de produits de recherche de haute qualité. Cherchez, trouvez et commandez des outils avec des données de validation étendues, des images, des références. Notre service clientèle scientifique est toujours à votre disposition si vous avez des questions sur la sélection ou l'application de nos produits.

Catégories Bestrophin 1 en vedette

Bestrophin 1 Anticorps

High quality antibodies with extensive validation data.

Bestrophin 1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Bestrophin 1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (4)
N° du produit ABIN7260777
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (4)
N° du produit ABIN1678855
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (2)
N° du produit ABIN7189978
Quantité 100 μL
Fiche technique Fiche technique

Bestrophin 1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6202076
Quantité 96 tests
Fiche technique Fiche technique

Bestrophin 1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346633
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1346631
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7419085
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits Bestrophin 1

Voisin, Monville, Plancheron, Balbous, Gaillard, Leveziel: "hRPE cells derived from induced pluripotent stem cells are more sensitive to oxidative stress than ARPE-19 cells." dans: Experimental eye research, Vol. 177, pp. 76-86, (2019) (PubMed).

Shahi, Hermans, Sinha, Brar, Moulton, Stulo, Borys, Capowski, Pillers, Gamm, Pattnaik: "Gene Augmentation and Readthrough Rescue Channelopathy in an iPSC-RPE Model of Congenital Blindness." dans: American journal of human genetics, Vol. 104, Issue 2, pp. 310-318, (2019) (PubMed).

Zhang, Kittredge, Ward, Ji, Chen, Yang: "ATP activates bestrophin ion channels through direct interaction." dans: Nature communications, Vol. 9, Issue 1, pp. 3126, (2018) (PubMed).

Shim, Kim, Lee, Lee, Kwon, Song: "Survival of Transplanted Human Embryonic Stem Cell-Derived Retinal Pigment Epithelial Cells in a Human Recipient for 22 Months." dans: JAMA ophthalmology, Vol. 135, Issue 3, pp. 287-290, (2017) (PubMed).

Uggenti, Briant, Streit, Thomson, Koay, Baines, Swanton, Manson: "Restoration of mutant bestrophin-1 expression, localisation and function in a polarised epithelial cell model." dans: Disease models & mechanisms, Vol. 9, Issue 11, pp. 1317-1328, (2016) (PubMed).

Parker, Mitrousis, Shoichet: "Hydrogel for Simultaneous Tunable Growth Factor Delivery and Enhanced Viability of Encapsulated Cells in Vitro." dans: Biomacromolecules, Vol. 17, Issue 2, pp. 476-84, (2016) (PubMed).

Kaneko, Pappas, Tajiri, Borlongan: "Oxytocin modulates GABAAR subunits to confer neuroprotection in stroke in vitro." dans: Scientific reports, Vol. 6, pp. 35659, (2016) (PubMed).

Kuo, Abdullaev, Hyzinski-García, Mongin: "Effects of alternative splicing on the function of bestrophin-1 calcium-activated chloride channels." dans: The Biochemical journal, Vol. 458, Issue 3, pp. 575-83, (2014) (PubMed).

Sharon, Al-Hamdani, Engelsberg, Mizrahi-Meissonnier, Obolensky, Banin, Sander, Jensen, Larsen, Schatz: "Ocular phenotype analysis of a family with biallelic mutations in the BEST1 gene." dans: American journal of ophthalmology, Vol. 157, Issue 3, pp. 697-709.e1-2, (2014) (PubMed).

Bertolotti, Neri, Camparini, Macaluso, Marigo: "Stem cells as source for retinal pigment epithelium transplantation." dans: Progress in retinal and eye research, Vol. 42, pp. 130-44, (2014) (PubMed).

Synonymes et noms alternatifs relatifs à Bestrophin 1

Bestrophin 1 (Best1), bestrophin 1 (BEST1), bestrophin 1 (best1), Bestrophin 1 (Bm1_25500), bestrophin 1 (Best1), anon-WO0118547.380, ARB, best, BEST, best-1, BEST1, BMD, Bmd, CG6264, Dbest, dBest1, dbest1, dmBest1, Dmel\\CG6264, mBest1, RP50, TU15B, VMD2, Vmd2

Protein level used designations for Bestrophin 1

  • Best1-PA
  • Best1-PB
  • Best1-PC
  • Best1-PD
  • CG6264-PA
  • CG6264-PB
  • CG6264-PC
  • CG6264-PD
  • bestrophin 1
  • bestrophin-1
  • Bestrophin 1
  • bestrophin-1-like
  • Best disease
  • Best1V1Delta2
  • vitelliform macular dystrophy protein 2
  • best macular dystrophy
  • vitelliform macular dystrophy 2 homolog
  • vitelliform macular dystrophy protein 2 homolog
  • vitelliform macular dystrophy (Best disease, bestrophin)
  • Bestrophin-1
Vous êtes ici:
Support technique