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beta Synuclein Produits

(Synuclein, beta (SNCB))

Catégories

The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease\; however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories beta Synuclein en vedette

beta Synuclein Anticorps

High quality antibodies with extensive validation data.

beta Synuclein Kits ELISA

Reliable ELISA kits for a wide range of species.

beta Synuclein Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

beta Synuclein recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7182802
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC, IF, ICC
Validations
  • (4)
N° du produit ABIN6265408
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
N° du produit ABIN652024
Quantité 400 μL
Fiche technique Fiche technique

beta Synuclein recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Dog, Human, Mouse, Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1110851
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4884595
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Cow
Analytical Method
Validations
N° du produit ABIN1123774
Quantité 96 tests
Fiche technique Fiche technique

beta Synuclein recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7125302
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320782
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1320784
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits beta Synuclein

Irvine, El-Agnaf, Shankar, Walsh: "Protein aggregation in the brain: the molecular basis for Alzheimer's and Parkinson's diseases." dans: Molecular medicine (Cambridge, Mass.), Vol. 14, Issue 7-8, pp. 451-64, (2008) (PubMed).

Wakabayashi, Tanji, Mori, Takahashi: "The Lewy body in Parkinson's disease: molecules implicated in the formation and degradation of alpha-synuclein aggregates." dans: Neuropathology : official journal of the Japanese Society of Neuropathology, Vol. 27, Issue 5, pp. 494-506, (2007) (PubMed).

Hashimoto, Bar-On, Ho, Takenouchi, Rockenstein, Crews, Masliah: "Beta-synuclein regulates Akt activity in neuronal cells. A possible mechanism for neuroprotection in Parkinson's disease." dans: The Journal of biological chemistry, Vol. 279, Issue 22, pp. 23622-9, (2004) (PubMed).

George: "The synucleins." dans: Genome biology, Vol. 3, Issue 1, pp. REVIEWS3002, (2002) (PubMed).

Giasson, Duda, Forman, Lee, Trojanowski: "Prominent perikaryal expression of alpha- and beta-synuclein in neurons of dorsal root ganglion and in medullary neurons." dans: Experimental neurology, Vol. 172, Issue 2, pp. 354-62, (2001) (PubMed).

Bruening, Giasson, Klein-Szanto, Lee, Trojanowski, Godwin: "Synucleins are expressed in the majority of breast and ovarian carcinomas and in preneoplastic lesions of the ovary." dans: Cancer, Vol. 88, Issue 9, pp. 2154-63, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à beta Synuclein

synuclein beta (SNCB), synuclein, beta (Sncb), synuclein, beta (sncb), synuclein beta (sncb), synuclein beta L homeolog (sncb.L), Beta-synuclein (syub), AI838531, betaSYN, LOC619281, MGC75784, sncb, SNCB, syub, zgc:66343

Protein level used designations for beta Synuclein

  • beta-synuclein
  • PNP 14
  • phosphoneuroprotein 14
  • zSyn-&beta
  • zSynC
  • synuclein, beta
  • putative beta-synuclein variant 1
  • Beta-synuclein
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