BMX Produits
(BMX Non-Receptor Tyrosine Kinase (BMX))
Catégories
This gene encodes a non-receptor tyrosine kinase belonging to the Tec kinase family. The protein contains a PH-like domain, which mediates membrane targeting by binding to phosphatidylinositol 3,4,5-triphosphate (PIP3), and a SH2 domain that binds to tyrosine-phosphorylated proteins and functions in signal transduction. The protein is implicated in several signal transduction pathways including the Stat pathway, and regulates differentiation and tumorigenicity of several types of cancer cells. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Sep 2009].
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Catégories BMX en vedette
BMX Anticorps
High quality antibodies with extensive validation data.
BMX Kits ELISA
Reliable ELISA kits for a wide range of species.
BMX Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BMX recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p), ICC, IHC (fro)
Validations
- (4)
N° du produit
ABIN7443482
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, ELISA, IF, ICC
Validations
- (4)
N° du produit
ABIN6261616
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, ELISA, IF
Validations
- (3)
N° du produit
ABIN7184420
Quantité
100 μL
Fiche technique
Fiche technique
BMX recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965180
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954117
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5691925
Quantité
2 x 96 tests
Fiche technique
Fiche technique
BMX recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1346793
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3134722
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3089858
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits BMX
: "BMX Negatively Regulates BAK Function, Thereby Increasing Apoptotic Resistance to Chemotherapeutic Drugs." dans: Cancer research, Vol. 75, Issue 7, pp. 1345-55, (2015) (PubMed).: "Estradiol modulates tumor necrosis factor-induced endothelial inflammation: role of tumor necrosis factor receptor 2." dans: Journal of vascular research, Vol. 50, Issue 1, pp. 21-34, (2012) (PubMed).
: "The tyrosine kinase BMX is an essential mediator of inflammatory arthritis in a kinase-independent manner." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 186, Issue 10, pp. 6014-23, (2011) (PubMed).
: "Bmx tyrosine kinase regulates TLR4-induced IL-6 production in human macrophages independently of p38 MAPK and NFkapp}B activity." dans: Blood, Vol. 111, Issue 4, pp. 1781-8, (2008) (PubMed).
: "Bone marrow X kinase-mediated signal transduction in irradiated vascular endothelium." dans: Cancer research, Vol. 68, Issue 8, pp. 2861-9, (2008) (PubMed).
: "A novel and evolutionarily conserved PtdIns(3,4,5)P3-binding domain is necessary for DOCK180 signalling." dans: Nature cell biology, Vol. 7, Issue 8, pp. 797-807, (2005) (PubMed).
: "Identification of phosphorylation sites within the SH3 domains of Tec family tyrosine kinases." dans: Biochimica et biophysica acta, Vol. 1645, Issue 2, pp. 123-32, (2003) (PubMed).
: "Functional interaction of caveolin-1 with Bruton's tyrosine kinase and Bmx." dans: The Journal of biological chemistry, Vol. 277, Issue 11, pp. 9351-7, (2002) (PubMed).
: "Interaction between tyrosine kinase Etk and a RUN domain- and FYVE domain-containing protein RUFY1. A possible role of ETK in regulation of vesicle trafficking." dans: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 30219-26, (2002) (PubMed).
: "Etk/Bmx as a tumor necrosis factor receptor type 2-specific kinase: role in endothelial cell migration and angiogenesis." dans: Molecular and cellular biology, Vol. 22, Issue 21, pp. 7512-23, (2002) (PubMed).
Synonymes et noms alternatifs relatifs à BMX
BMX non-receptor tyrosine kinase (BMX), BMX non-receptor tyrosine kinase (bmx), BMX non-receptor tyrosine kinase (Bmx), BMX, ETK, Etk, Etk/Bmx, PSCTK2, PSCTK3, RGD1565643, Tyro8Protein level used designations for BMX
- BMX non-receptor tyrosine kinase
- cytoplasmic tyrosine-protein kinase BMX-like
- BTK-like on X chromosome
- Etk/Bmx cytosolic tyrosine kinase
- NTK38 tyrosine kinase
- bone marrow tyrosine kinase gene in chromosome X protein
- cytoplasmic tyrosine-protein kinase BMX
- epithelial and endothelial tyrosine kinase
- TYRO8 protein tyrosine kinase 8
- bone marrow tyrosine kinase gene in chromosome X protein homolog
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