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BMPR1B Produits

(Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Catégories

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].

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Catégories BMPR1B en vedette

BMPR1B Anticorps

High quality antibodies with extensive validation data.

BMPR1B Kits ELISA

Reliable ELISA kits for a wide range of species.

BMPR1B Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BMPR1B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN3022720
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (5)
N° du produit ABIN7260047
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
N° du produit ABIN7145708
Quantité 100 μg
Fiche technique Fiche technique

BMPR1B recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954155
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4881803
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1123996
Quantité 96 tests
Fiche technique Fiche technique

BMPR1B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (2)
N° du produit ABIN1346785
Quantité 2 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (2)
N° du produit ABIN5569802
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN7194418
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits BMPR1B

Tengroth, Arebro, Larsson, Bachert, Georén, Cardell: "Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps." dans: Scientific reports, Vol. 8, Issue 1, pp. 1561, (2018) (PubMed).

Ferguson, Van Handel, Bay, Fiziev, Org, Lee, Shkhyan, Banks, Scheinberg, Wu, Saitta, Elphingstone, Larson, Riester, Pyle, Bernthal, Mikkola, Ernst, van Wijnen, Bonaguidi, Evseenko: "Mapping molecular landmarks of human skeletal ontogeny and pluripotent stem cell-derived articular chondrocytes." dans: Nature communications, Vol. 9, Issue 1, pp. 3634, (2018) (PubMed).

Toofan, Busch, Morrison, OBrien, Jørgensen, Copland, Wheadon: "Chronic myeloid leukaemia cells require the bone morphogenic protein pathway for cell cycle progression and self-renewal." dans: Cell death & disease, Vol. 9, Issue 9, pp. 927, (2018) (PubMed).

Hegarty, Sullivan, OKeeffe: "Endocytosis contributes to BMP2-induced Smad signalling and neuronal growth." dans: Neuroscience letters, Vol. 643, pp. 32-37, (2017) (PubMed).

Wang, He, Zhang, Shi, Dong, Pei, Zhu: "A Selective Cell Population From Dermis Strengthens Bone Regeneration." dans: Stem cells translational medicine, (2016) (PubMed).

Chung, Gao, Jegga, Das: "Estrogen mediated epithelial proliferation in the uterus is directed by stromal Fgf10 and Bmp8a." dans: Molecular and cellular endocrinology, Vol. 400, pp. 48-60, (2015) (PubMed).

Srikanth, Kim, Das, Kessler: "BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells." dans: Molecular cancer research : MCR, Vol. 12, Issue 2, pp. 283-94, (2014) (PubMed).

He, Dong, Wang, Xu, Dai, Ma, Zhu: "Bone morphogenetic protein receptor IB as a marker for enrichment of osteogenic precursor-like cells in human dermis." dans: Archives of dermatological research, Vol. 303, Issue 8, pp. 581-90, (2011) (PubMed).

Kan, Liu, McGuire, Berger, Awatramani, Dymecki, Kessler: "Dysregulation of local stem/progenitor cells as a common cellular mechanism for heterotopic ossification." dans: Stem cells (Dayton, Ohio), Vol. 27, Issue 1, pp. 150-6, (2009) (PubMed).

Nicholls, Harrison, Gilchrist, Farnworth, Stanton: "Growth differentiation factor 9 is a germ cell regulator of Sertoli cell function." dans: Endocrinology, Vol. 150, Issue 5, pp. 2481-90, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à BMPR1B

bone morphogenetic protein receptor type 1B (BMPR1B), bone morphogenetic protein receptor type 1B (bmpr1b), bone morphogenetic protein receptor, type IBb (bmpr1bb), bone morphogenetic protein receptor, type 1B (Bmpr1b), bone morphogenetic protein receptor, type IBa (bmpr1ba), bone morphogenetic protein receptor type 1B (Bmpr1b), Acvrlk6, AI385617, alk-6, ALK-6, ALK6, alk6, Alk6, alk6b, alk6tr, AV355320, BMP15, BMPR-1B, BMPR-IB, BMPR1B, bmpr1b, BMPRIB, BR1b, cdw293, CDw293, CFK-43a, FecB, RPK-1, SKR6, zALK-6, zgc:92220, zgc:172219

Protein level used designations for BMPR1B

  • BMP receptor IB
  • activin receptor-like kinase 6
  • bone morphogenetic protein receptor type-1B
  • bone morphogenetic protein receptor, type IB
  • bone morphogenetic protein receptor type IB,b
  • bone morphogenetic protein receptor type-1B-like
  • BMP type-1B receptor
  • serine/threonine-protein kinase receptor R6
  • alk6
  • bone morphogenetic protein receptor, type 1b
  • BMPR-1B
  • serine/threonine receptor kinase
  • bone morphogenetic protein receptor IB
  • bone morphogenetic protein binding serine/threonine kinase receptor
  • ALK-6
  • SKR6
  • receptor protein kinase
  • bone morphogenetic protein receptor 1B
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