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BMPR2 Produits

(Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))

Catégories

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008].

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Catégories BMPR2 en vedette

BMPR2 Anticorps

High quality antibodies with extensive validation data.

BMPR2 Kits ELISA

Reliable ELISA kits for a wide range of species.

BMPR2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

BMPR2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Monkey, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (2)
  • (4)
N° du produit ABIN968987
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Monkey, Mouse, Rat
Application WB, ELISA, IHC, ICC
Validations
  • (2)
  • (4)
N° du produit ABIN968988
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, IHC, FACS
Validations
  • (7)
N° du produit ABIN3030192
Quantité 0.4 mL
Fiche technique Fiche technique

BMPR2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6965212
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6962060
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954156
Quantité 96 tests
Fiche technique Fiche technique

BMPR2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1346791
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7505025
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Human Cells
Validations
N° du produit ABIN7318203
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits BMPR2

Hanusek, Rybicka, Popławski, Adamiok-Ostrowska, Głuchowska, Piekiełko-Witkowska, Bogusławska: "TGF‑β1 affects the renal cancer miRNome and regulates tumor cells proliferation." dans: International journal of molecular medicine, Vol. 49, Issue 4, (2022) (PubMed).

Liu, Zhong, Yuan, Chen, Zhou, An, Guo, Fan, Li, Sun, Li, Shi, Weng: "MicroRNA-155 inhibits the osteogenic differentiation of mesenchymal stem cells induced by BMP9 via downregulation of BMP signaling pathway." dans: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3379-3393, (2018) (PubMed).

Shi, Zhu, Wei, Fu, Wang, Liu, Zhang, Liang, Xing, Wang, Wang: "Baicalein attenuates monocrotaline-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition." dans: Life sciences, Vol. 207, pp. 442-450, (2018) (PubMed).

Bollum, Huse, Oksvold, Bai, Hilden, Forfang, Yoon, Wälchli, Smeland, Myklebust: "BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5." dans: PLoS ONE, Vol. 12, Issue 5, pp. e0177188, (2017) (PubMed).

Hegarty, Sullivan, OKeeffe: "Endocytosis contributes to BMP2-induced Smad signalling and neuronal growth." dans: Neuroscience letters, Vol. 643, pp. 32-37, (2017) (PubMed).

Lynch, Ahsan: "Correlating the Effects of Bone Morphogenic Protein to Secreted Soluble Factors from Fibroblasts and Mesenchymal Stem Cells in Regulating Regenerative Processes In Vitro." dans: Tissue engineering. Part A, (2014) (PubMed).

Srikanth, Kim, Das, Kessler: "BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells." dans: Molecular cancer research : MCR, Vol. 12, Issue 2, pp. 283-94, (2014) (PubMed).

Wang, Kahaleh: "Epigenetic repression of bone morphogenetic protein receptor II expression in scleroderma." dans: Journal of cellular and molecular medicine, Vol. 17, Issue 10, pp. 1291-9, (2014) (PubMed).

Li, Cao, Ma, Wang, Zhang, Luo, Chen, Wu, Meng, Zhang, Yuan, Ma, Huang: "Roles of miR-1-1 and miR-181c in ventricular septal defects." dans: International journal of cardiology, Vol. 168, Issue 2, pp. 1441-6, (2013) (PubMed).

Fong, Bisson, Laberge, McManus, Grenier, Faucheux, Roux: "Bone morphogenetic protein-9 activates Smad and ERK pathways and supports human osteoclast function and survival in vitro." dans: Cellular signalling, Vol. 25, Issue 4, pp. 717-28, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à BMPR2

bone morphogenetic protein receptor type 2 (BMPR2), bone morphogenetic protein receptor, type II b (serine/threonine kinase) (bmpr2b), bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), bone morphogenetic protein receptor type 2 (Bmpr2), 2610024H22Rik, AL117858, AW546137, BB189135, BMP-2, BMPR-2, BMPR-II, Bmpr-II, BMPR3, BMPRII, bmprii, BMR2, BRK-3, Gm20272, PPH1, T-ALK

Protein level used designations for BMPR2

  • bone morphogenetic protein receptor type II
  • bone morphogenetic protein receptor type-2
  • bone morphogenetic protein receptor type II b
  • BMP type II receptor
  • BMP type-2 receptor
  • BMPR-2
  • type II activin receptor-like kinase
  • type II receptor for bone morphogenetic protein-4
  • bone morphogenic protein receptor, type II (serine/threonine kinase)
  • bone morphogenic protein receptor type 2
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