BMPR2 Produits
(Bone Morphogenetic Protein Receptor, Type II (serine/threonine Kinase) (BMPR2))
Catégories
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008].
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Catégories BMPR2 en vedette
BMPR2 Anticorps
High quality antibodies with extensive validation data.
BMPR2 Kits ELISA
Reliable ELISA kits for a wide range of species.
BMPR2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BMPR2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
- (4)
N° du produit
ABIN968987
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IHC, ICC
Validations
- (2)
- (4)
N° du produit
ABIN968988
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (2)
- (4)
N° du produit
ABIN542871
Quantité
400 μL
Fiche technique
Fiche technique
BMPR2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6965212
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962060
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954156
Quantité
96 tests
Fiche technique
Fiche technique
BMPR2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1346791
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5569816
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505025
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits BMPR2
: "TGF‑β1 affects the renal cancer miRNome and regulates tumor cells proliferation." dans: International journal of molecular medicine, Vol. 49, Issue 4, (2022) (PubMed).: "MicroRNA-155 inhibits the osteogenic differentiation of mesenchymal stem cells induced by BMP9 via downregulation of BMP signaling pathway." dans: International journal of molecular medicine, Vol. 41, Issue 6, pp. 3379-3393, (2018) (PubMed).
: "Baicalein attenuates monocrotaline-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition." dans: Life sciences, Vol. 207, pp. 442-450, (2018) (PubMed).
: "BMP-7 induces apoptosis in human germinal center B cells and is influenced by TGF-β receptor type I ALK5." dans: PLoS ONE, Vol. 12, Issue 5, pp. e0177188, (2017) (PubMed).
: "Endocytosis contributes to BMP2-induced Smad signalling and neuronal growth." dans: Neuroscience letters, Vol. 643, pp. 32-37, (2017) (PubMed).
: "Correlating the Effects of Bone Morphogenic Protein to Secreted Soluble Factors from Fibroblasts and Mesenchymal Stem Cells in Regulating Regenerative Processes In Vitro." dans: Tissue engineering. Part A, (2014) (PubMed).
: "BMP signaling induces astrocytic differentiation of clinically derived oligodendroglioma propagating cells." dans: Molecular cancer research : MCR, Vol. 12, Issue 2, pp. 283-94, (2014) (PubMed).
: "Epigenetic repression of bone morphogenetic protein receptor II expression in scleroderma." dans: Journal of cellular and molecular medicine, Vol. 17, Issue 10, pp. 1291-9, (2014) (PubMed).
: "Roles of miR-1-1 and miR-181c in ventricular septal defects." dans: International journal of cardiology, Vol. 168, Issue 2, pp. 1441-6, (2013) (PubMed).
: "Bone morphogenetic protein-9 activates Smad and ERK pathways and supports human osteoclast function and survival in vitro." dans: Cellular signalling, Vol. 25, Issue 4, pp. 717-28, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à BMPR2
bone morphogenetic protein receptor type 2 (BMPR2), bone morphogenetic protein receptor, type II b (serine/threonine kinase) (bmpr2b), bone morphogenetic protein receptor, type II (serine/threonine kinase) (Bmpr2), bone morphogenetic protein receptor type 2 (Bmpr2), 2610024H22Rik, AL117858, AW546137, BB189135, BMP-2, BMPR-2, BMPR-II, Bmpr-II, BMPR3, BMPRII, bmprii, BMR2, BRK-3, Gm20272, PPH1, T-ALKProtein level used designations for BMPR2
- bone morphogenetic protein receptor type II
- bone morphogenetic protein receptor type-2
- bone morphogenetic protein receptor type II b
- BMP type II receptor
- BMP type-2 receptor
- BMPR-2
- type II activin receptor-like kinase
- type II receptor for bone morphogenetic protein-4
- bone morphogenic protein receptor, type II (serine/threonine kinase)
- bone morphogenic protein receptor type 2
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