BPDE-DNA anticorps
L’anticorps Souris Monoclonal anti-BPDE-DNA a été validé pour EIA, IF, IHC (p) et IP. Il convient pour détecter BPDE-DNA dans des échantillons de Mammifères.
N° du produit ABIN1105553
Aperçu rapide pour BPDE-DNA anticorps (ABIN1105553)
Antigène
BPDE-DNA
(Benzo[a]pyrenediol Epoxide Modified DNA (BPDE-DNA))
Reactivité
Mammifères
Hôte
Souris
Clonalité
Monoclonal
Application
Enzyme Immunoassay (EIA), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
Clone
5D11
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Purification
- Protein G
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Immunogène
- BPDE-I-DNA complexed with methylated BSA
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 0.1 mg/mL
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Buffer
- PBS, 0.02 % sodium azide, 0.1 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store at 2 - 8 °C.
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- BPDE-DNA (Benzo[a]pyrenediol Epoxide Modified DNA (BPDE-DNA))
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Autre désignation
- BPDE-DNA
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Sujet
- A number of chemicals, including polycyclic aromatic hydrocarbons (PAHs), have been shown to bind to DNA. This DNA damage can occur both early and late in the malignant process, thereby acting as an initiator and assisting in the progression of tumors. PAHs are released into the environment following incomplete combustion of organic materials. The most common sources of PAHs are from smoking and from consuming broiled or grilled foods. Human exposure to PAHs comes from various occupational, environmental, dietary and medicinal sources. Benzo[a]pyrene is a representative PAH. Antibodies to benzo[a]pyrenediol-epoxide modified DNA (BPDE-DNA) can be used to identify polycyclic aromatic hydrocarbon (PAH)-DNA adducts. Exposure to this group of compounds is believed to be carcinogenic.
Antigène
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