BRAF Produits
(B-Raf proto-oncogene, serine/threonine kinase (BRAF))
Catégories
This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008].
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Catégories BRAF en vedette
BRAF Anticorps
High quality antibodies with extensive validation data.
BRAF Kits ELISA
Reliable ELISA kits for a wide range of species.
BRAF Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
BRAF recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Monkey
Application
WB, IHC, IHC (p), IF, FACS
Validations
- (9)
N° du produit
ABIN1496951
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Dog, Human, Monkey, Rat
Application
WB, IHC, IHC (p), IF
Validations
- (8)
N° du produit
ABIN1496954
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Dog, Human
Application
WB, IHC, IHC (p)
Validations
- (18)
N° du produit
ABIN1496961
Quantité
100 μL
Fiche technique
Fiche technique
BRAF recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6962346
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6954037
Quantité
96 tests
Fiche technique
Fiche technique
BRAF recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (2)
N° du produit
ABIN5570026
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (2)
N° du produit
ABIN5570024
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
N° du produit
ABIN5570017
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits BRAF
: "Protein expression of KIT, BRAF, GNA11, GNAQ and RASSF1 in feline diffuse iris melanomas." dans: Veterinary journal (London, England : 1997), Vol. 249, pp. 33-40, (2019) (PubMed).: "Newly Identified BRAF Mutation in Rheumatoid Arthritis." dans: Arthritis & rheumatology (Hoboken, N.J.), Vol. 68, Issue 6, pp. 1377-83, (2016) (PubMed).
: "Histologic and immunohistochemical predictors of clinical behavior for feline diffuse iris melanoma." dans: Veterinary ophthalmology, Vol. 19 Suppl 1, pp. 44-55, (2016) (PubMed).
: "The epithelial polarity regulator LGALS9/galectin-9 induces fatal frustrated autophagy in KRAS mutant colon carcinoma that depends on elevated basal autophagic flux." dans: Autophagy, Vol. 11, Issue 8, pp. 1373-88, (2015) (PubMed).
: "HNF4? is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer." dans: Gut, (2014) (PubMed).
: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).
: "TRIM59, a novel multiple cancer biomarker for immunohistochemical detection of tumorigenesis." dans: BMJ open, Vol. 2, Issue 5, (2012) (PubMed).
: "BRAF drives synovial fibroblast transformation in rheumatoid arthritis." dans: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34299-303, (2010) (PubMed).
: "Calcineurin increases glucose activation of ERK1/2 by reversing negative feedback." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 51, pp. 22314-9, (2010) (PubMed).
: "Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer." dans: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 26, Issue 35, pp. 5705-12, (2008) (PubMed).
Synonymes et noms alternatifs relatifs à BRAF
B-Raf proto-oncogene, serine/threonine kinase (BRAF), B-Raf proto-oncogene, serine/threonine kinase (Braf), B-Raf proto-oncogene, serine/threonine kinase S homeolog (braf.S), B-Raf proto-oncogene, serine/threonine kinase (braf), Braf transforming gene (Braf), si:dkey-222f8.3 (si:dkey-222f8.3), 9930012E13Rik, AA120551, AA387315, AA473386, B-Raf, B-raf, B-RAF1, b-raf1, BRAF, braf, Braf-2, BRAF1, braf1, Braf2, C-RMIL, C87398, C230098H17, D6Ertd631e, fc48g01, NS7, RAFB1, rafb1, RMIL, sierrabraf, wu:fc48g01Protein level used designations for BRAF
- 94 kDa B-raf protein
- B-Raf proto-oncogene serine/threonine-protein kinase (p94)
- murine sarcoma viral (v-raf) oncogene homolog B1
- proto-oncogene B-Raf
- serine/threonine-protein kinase B-raf
- v-raf murine sarcoma viral oncogene homolog B1
- B-Raf
- B-Raf proto-oncogene serine/threonine-protein kinase
- proto-oncogene c-Rmil
- rmil serine/threonine-protein kinase
- serine/threonine kinase
- serine/threonine-protein kinase Rmil
- serine/threonine protein kinase BRAF
- serine/threonine-protein kinase B-raf-like
- B-raf protein
- uncharacterized protein LOC561722
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