Cathepsin B Protéines
(Cathepsin B (CTSB))
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
| Catalog no. | Produit | Reactivité | Hôte / Clonalité | Application | Prix et délai de livraison |
|---|---|---|---|---|---|
| Cathepsin B Protein (CTSB) (AA 18-339) (His tag) | Souris | Baculovirus infected Insect Cells |
|
907,69 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 18-339) (His tag) | Souris | Baculovirus infected Insect Cells |
|
815,38 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 18-339, full length) (His tag) | Humain | Mammalian Cells |
|
407,00 €
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|
|
| Cathepsin B Protein (CTSB) (AA 1-339) (His tag) | Rat | HEK-293 Cells |
|
962,00 €
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|
|
| Cathepsin B Protein (CTSB) (His tag) | Souris | HEK-293 Cells |
|
866,00 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 1-339) (GST tag) | Humain | Wheat germ |
|
624,00 €
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|
|
| Cathepsin B Protein (CTSB) (AA 21-339) (GST tag) | Humain | Wheat germ |
|
624,00 €
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|
|
| Cathepsin B Protein (CTSB) (AA 18-339) (His tag) | Souris | HEK-293 Cells |
|
479,60 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 18-339) (His tag) | Souris | Mammalian Cells |
|
731,38 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) | Humain | Human |
|
863,12 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 18-339) (His tag) | Souris | Mammalian Cells |
|
615,38 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 18-339) (His tag) | Humain | Human Cells |
|
608,79 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 18-339) (His tag) | Humain | HEK-293 Cells |
|
866,00 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (His tag) | Humain | Mammalian Cells |
|
1.778,00 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 18-333) (His tag) | Souris | Mammalian Cells |
|
1.778,00 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 18-333) (Fc Tag) | Souris | Mammalian Cells |
|
1.778,00 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 18-339) (His tag) | Humain | HEK-293 Cells |
|
395,60 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 129-333) (His tag) | Humain | Escherichia coli (E. coli) |
|
565,29 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 129-333) (His tag) | Souris | Escherichia coli (E. coli) |
|
717,91 €
Voir le prix
|
|
| Cathepsin B Protein (CTSB) (AA 129-333) (His tag) | Rat | Escherichia coli (E. coli) |
|
763,69 €
Voir le prix
|
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- EAA (Enzyme Activity Assay: Application indiquée)
- Origine
- Souris
- Hôte
- Baculovirus infected Insect Cells
- Type Proteine
- Recombinant
- Pureté
- > 90 %
- Activité biologique
- Active
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- Origine
- Souris
- Hôte
- Baculovirus infected Insect Cells
- Type Proteine
- Recombinant
- Pureté
- > 90 %
Protein
- SDS (SDS-PAGE: Image de validation disponible)
- Origine
- Humain
- Hôte
- Mammalian Cells
- Type Proteine
- Recombinant
- Pureté
- Greater than 95 % as determined by SDS-PAGE.
Protein
- WB (Western Blotting: Image de validation disponible)
- Origine
- Rat
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
Protein
- WB (Western Blotting: Image de validation disponible)
- Origine
- Souris
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- Activité biologique
- Active
Protein
- AP (Affinity Purification: Application indiquée)
- AA (Antibody Array: Application indiquée)
- ELISA (ELISA: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Origine
- Humain
- Hôte
- Wheat germ
- Type Proteine
- Recombinant
Protein
- AP (Affinity Purification: Application indiquée)
- AA (Antibody Array: Application indiquée)
- ELISA (ELISA: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Origine
- Humain
- Hôte
- Wheat germ
- Type Proteine
- Recombinant
Protein
- WB (Western Blotting: Image de validation disponible)
- Origine
- Souris
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- ELISA (ELISA: Application indiquée)
- AcA (Activity Assay: Application indiquée)
- Origine
- Souris
- Hôte
- Mammalian Cells
- Type Proteine
- Recombinant
- Pureté
- >90 % as determined by SDS-PAGE.
- Activité biologique
- Active
Protein
- Origine
- Humain
- Hôte
- Human
- Type Proteine
- Native
- Pureté
- > 98 % pure
- Activité biologique
- Active
Protein
- WB (Western Blotting: Application indiquée)
- ELISA (ELISA: Application indiquée)
- Origine
- Souris
- Hôte
- Mammalian Cells
- Type Proteine
- Recombinant
- Pureté
- Greater than 95 % as determined by SDS-PAGE.
Protein
- Origine
- Humain
- Hôte
- Human Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 97 % as determined by reducing SDS-PAGE.
- Activité biologique
- Active
Protein
- Imm (Immunogen: Application indiquée)
- Origine
- Humain
- Hôte
- Mammalian Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
Protein
- Imm (Immunogen: Application indiquée)
- Origine
- Souris
- Hôte
- Mammalian Cells
- Type Proteine
- Recombinant
- Pureté
- > 90 % as determined by reducing SDS-PAGE.
Protein
- Imm (Immunogen: Application indiquée)
- Origine
- Souris
- Hôte
- Mammalian Cells
- Type Proteine
- Recombinant
- Pureté
- > 90 % as determined by reducing SDS-PAGE.
Protein
- Origine
- Humain
- Hôte
- HEK-293 Cells
- Type Proteine
- Recombinant
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- PC (Positive Control: Application indiquée)
- Origine
- Humain
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 90 %
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- PC (Positive Control: Application indiquée)
- Origine
- Souris
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 95 %
Protein
- SDS (SDS-PAGE: Application indiquée)
- WB (Western Blotting: Application indiquée)
- Imm (Immunogen: Application indiquée)
- PC (Positive Control: Application indiquée)
- Origine
- Rat
- Hôte
- Escherichia coli (E. coli)
- Type Proteine
- Recombinant
- Pureté
- > 90 %
Dernières publications pour nos Cathepsin B Protéines
: "Characterization of Novel Piperidine-Based Inhibitor of Cathepsin B-Dependent Bacterial Toxins and Viruses." dans: ACS infectious diseases, Vol. 4, Issue 8, pp. 1235-1245, (2018) (PubMed).
: "Cysteine protease cathepsin B mediates radiation-induced bystander effects." dans: Nature, Vol. 547, Issue 7664, pp. 458-462, (2017) (PubMed).
: "Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting." dans: Scientific reports, Vol. 5, pp. 13476, (2015) (PubMed).
: "Prodrug-inspired probes selective to cathepsin B over other cysteine cathepsins." dans: Journal of medicinal chemistry, Vol. 57, Issue 14, pp. 6092-104, (2014) (PubMed).
: "Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage." dans: Cell research, Vol. 24, Issue 3, pp. 344-58, (2014) (PubMed).
: "Human gastric adenocarcinoma cathepsin B: isolation and sequencing of full-length cDNAs and polymorphisms of the gene." dans: Gene, Vol. 139, Issue 2, pp. 163-9, (1994) (PubMed).
: "Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 20, pp. 7721-5, (1986) (PubMed).
: "Cysteine protease cathepsin B mediates radiation-induced bystander effects." dans: Nature, Vol. 547, Issue 7664, pp. 458-462, (2017) (PubMed).
: "Identification of agents effective against multiple toxins and viruses by host-oriented cell targeting." dans: Scientific reports, Vol. 5, pp. 13476, (2015) (PubMed).
: "Prodrug-inspired probes selective to cathepsin B over other cysteine cathepsins." dans: Journal of medicinal chemistry, Vol. 57, Issue 14, pp. 6092-104, (2014) (PubMed).
: "Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage." dans: Cell research, Vol. 24, Issue 3, pp. 344-58, (2014) (PubMed).
: "Human gastric adenocarcinoma cathepsin B: isolation and sequencing of full-length cDNAs and polymorphisms of the gene." dans: Gene, Vol. 139, Issue 2, pp. 163-9, (1994) (PubMed).
: "Nucleotide and predicted amino acid sequences of cloned human and mouse preprocathepsin B cDNAs." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 83, Issue 20, pp. 7721-5, (1986) (PubMed).
Pseudonymes pour Cathepsin B Protéines
cathepsin B (CTSB) Protéinescathepsin B (Ctsb) Protéines
cathepsin B S homeolog (ctsb.S) Protéines
cathepsin B (LOC692390) Protéines
APPS Protéines
apps Protéines
CB Protéines
CPSB Protéines
cpsb Protéines
CTSB Protéines
LOC692390 Protéines
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