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c-MET Produits

(Met Proto-Oncogene (MET))

Catégories

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories c-MET en vedette

c-MET Anticorps

High quality antibodies with extensive validation data.

c-MET Kits ELISA

Reliable ELISA kits for a wide range of species.

c-MET Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

c-MET recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (5)
  • (5)
N° du produit ABIN671661
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Monkey
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (7)
N° du produit ABIN5542707
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (5)
N° du produit ABIN7434734
Quantité 100 μL
Fiche technique Fiche technique

c-MET recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (5)
N° du produit ABIN625228
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (4)
N° du produit ABIN5680031
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (4)
N° du produit ABIN625241
Quantité 96 tests
Fiche technique Fiche technique

c-MET recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
N° du produit ABIN7275248
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7275247
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7275246
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits c-MET

Mahameed, Boukeileh, Obiedat, Darawshi, Dipta, Rimon, McLennan, Fassler, Reichmann, Karni, Preisinger, Wilhelm, Huber, Tirosh: "Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy." dans: Nature communications, Vol. 11, Issue 1, pp. 1304, (2020) (PubMed).

Mahameed, Wilhelm, Darawshi, Obiedat, Tommy, Chintha, Schubert, Samali, Chevet, Eriksson, Huber, Tirosh: "The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors." dans: Cell death & disease, Vol. 10, Issue 4, pp. 300, (2020) (PubMed).

Yoo, Lee, Jung, Han, Lee, Han, Kim, Chae, Ryu, Chung: "Machine Learning-Guided Prediction of Antigen-Reactive In Silico Clonotypes Based on Changes in Clonal Abundance through Bio-Panning." dans: Biomolecules, Vol. 10, Issue 3, (2020) (PubMed).

Novo, Heath, Mitchell, Caligiuri, MacFarlane, Reijmer, Charlton, Knight, Calka, McGhee, Dornier, Sumpton, Mason, Echard, Klinkert, Secklehner, Kruiswijk, Vousden, Macpherson, Blyth, Bailey, Yin et al.: "Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels. ..." dans: Nature communications, Vol. 9, Issue 1, pp. 5069, (2019) (PubMed).

Penchev, Chang, Begum, Ewachiw, Gocke, Li, McMillan, Wang, Anders, Marchionni, Maitra, Uren, Rasheed, Matsui: "Ezrin Promotes Stem Cell Properties in Pancreatic Ductal Adenocarcinoma." dans: Molecular cancer research : MCR, Vol. 17, Issue 4, pp. 929-936, (2019) (PubMed).

Stringer, Day, DSouza, Jamieson, Ensbey, Bruce, Lim, Goasdoué, Offenhäuser, Akgül, Allan, Robertson, Lucas, Tollesson, Campbell, Winter, Do, Dobrovic, Inglis, Jeffree, Johns, Boyd: "A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma." dans: Scientific reports, Vol. 9, Issue 1, pp. 4902, (2019) (PubMed).

Graves-Deal, Bogatcheva, Rehman, Lu, Higginbotham, Singh: "Broad-spectrum receptor tyrosine kinase inhibitors overcome de novo and acquired modes of resistance to EGFR-targeted therapies in colorectal cancer." dans: Oncotarget, Vol. 10, Issue 13, pp. 1320-1333, (2019) (PubMed).

Li, Dick, Lu, Zhang, Sun: "Induction of MET Receptor Tyrosine Kinase Down-regulation through Antibody-mediated Receptor Clustering." dans: Scientific reports, Vol. 9, Issue 1, pp. 1988, (2019) (PubMed).

Jo, Lee, Lee, Park, Park, Choi, Hong, Kim: "Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells." dans: BMC cancer, Vol. 19, Issue 1, pp. 496, (2019) (PubMed).

Ma, Zhang, Wang, Huang, Kuai, Zhu, Chen, Jia, Feng, Tang, Liu: "High-Affinity Human Anti-c-Met IgG Conjugated to Oxaliplatin as Targeted Chemotherapy for Hepatocellular Carcinoma." dans: Frontiers in oncology, Vol. 9, pp. 717, (2019) (PubMed).

Synonymes et noms alternatifs relatifs à c-MET

MET proto-oncogene, receptor tyrosine kinase (MET), met proto-oncogene (Met), MET proto-oncogene, receptor tyrosine kinase (Met), MET proto-oncogene, receptor tyrosine kinase L homeolog (met.L), AI838057, AUTS9, c-Met, c-met, C-MET, HGF, HGFR, Hgfr, MET, met, met-A, Par4, RCCP2

Protein level used designations for c-MET

  • HGF receptor
  • HGF/SF receptor
  • SF receptor
  • hepatocyte growth factor receptor
  • met proto-oncogene tyrosine kinase
  • proto-oncogene c-Met
  • scatter factor receptor
  • tyrosine-protein kinase Met
  • c-Met
  • hepatocyte growth factor receptor-like
  • met proto-oncogene
  • Proto-oncogene c-Met
  • Scatter factor receptor
  • Tyrosine-protein kinase Met
  • Hepatocyte growth factor receptor
  • HGF receptor c-Met
  • proto-oncogene, receptor tyrosine kinase
  • tyrosine kinase
  • met proto-oncogene (hepatocyte growth factor receptor)
  • MET proto-oncogene, receptor tyrosine kinase L homeolog
  • c-met/hepatocyte growth factor receptor
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