Recombinant c-MET anticorps (C-Term)

N° du produit ABIN7795683

L’anticorps anti-c-MET Monoclonal Lapin est utilisé pour la détection de c-MET dans des échantillons de Humain. Il a été validé pour WB, IHC, FACS, ICC et IP.

Aperçu rapide pour Recombinant c-MET anticorps (C-Term) (ABIN7795683)

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp c-MET est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunoprecipitation (IP)

Clone: BLR283L

Détail du produit anti-c-MET anticorps

Épitope: C-Term

Fonction: Rabbit anti-Met Recombinant Monoclonal Antibody [BLR283L]

Purification: Purified

Immunogène: Between 1340 and C-terminus

Isotype: IgG

Information d'application

Indications d'application: Flow-Cyt,Fixed in 4 % formaldehyde and permeabilized with 90 % methanol. 0.5 μL per 1 x 10^6 cells.,ICC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.,IHC,1100 to 1500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.,IP,6 μL/mg lysate ,WB,11000

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1000 μg/mL

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: 2 - 8 °C

Date de péremption: 12 months

Détails sur c-MET

Antigène: c-MET (MET) (Met Proto-Oncogene (MET))

Autre désignation: Met

Sujet: The proto-oncogene MET is a member of the receptor tyrosine kinase family of proteins. The preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. [taken from NCBI Entrez Gene (Gene ID: 4233)].

ID gène: 4233

UniProt: P08581

Pathways: Signalisation RTK, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor