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CBS Produits

(Cystathionine-beta-Synthase (CBS))

Catégories

The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010].

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Catégories CBS en vedette

CBS Anticorps

High quality antibodies with extensive validation data.

CBS Kits ELISA

Reliable ELISA kits for a wide range of species.

CBS Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CBS recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p), IP, RNAi
Validations
  • (38)
  • (8)
N° du produit ABIN7489109
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (2)
  • (6)
N° du produit ABIN3021959
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IF, IHC (p), FACS
Validations
  • (2)
  • (5)
N° du produit ABIN1881141
Quantité 400 μL
Fiche technique Fiche technique

CBS recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6974522
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966188
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966187
Quantité 96 tests
Fiche technique Fiche technique

CBS recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (4)
  • (1)
N° du produit ABIN1348191
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1348197
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1348195
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CBS

Veerareddy, Dao, Yun, Stokes, Disbrow, Kevil, Cvek, Trutschl, Kilgore, Ramanathan, Zivadinov, Alexander: "Dysregulated Sulfide Metabolism in Multiple Sclerosis: Serum and Vascular Endothelial Inflammatory Responses." dans: Pathophysiology : the official journal of the International Society for Pathophysiology, Vol. 29, Issue 3, pp. 570-582, (2022) (PubMed).

Fling, Doskey, Fader, Nault, Zacharewski: "2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice." dans: Scientific reports, Vol. 10, Issue 1, pp. 14831, (2021) (PubMed).

Kuai, Luo, Qu, Ru, Luo, Ding, Xing, Liu, Sun, Li, Li: "Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model." dans: Frontiers in pharmacology, Vol. 12, pp. 632414, (2021) (PubMed).

Niu, Wang, Qian, Wang, Wu, Chen, Yan: "Allosteric control of human cystathionine β-synthase activity by a redox active disulfide bond." dans: The Journal of biological chemistry, Vol. 293, Issue 7, pp. 2523-2533, (2018) (PubMed).

Seale, Ha, Hashimoto, Berry: "Relationship between selenoprotein P and selenocysteine lyase: Insights into selenium metabolism." dans: Free radical biology & medicine, Vol. 127, pp. 182-189, (2018) (PubMed).

Grassi, Tyagi, Calvert, Gambari, Walker, Yu, Robinson, Li, Lisignoli, Vaccaro, Adams, Pacifici: "Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency." dans: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 5, pp. 949-63, (2016) (PubMed).

Shang, Siow, Isaak, O: "Downregulation of Glutathione Biosynthesis Contributes to Oxidative Stress and Liver Dysfunction in Acute Kidney Injury." dans: Oxidative medicine and cellular longevity, Vol. 2016, pp. 9707292, (2016) (PubMed).

Chen, Wang, Li, Jiang, Lu, Zhou: "Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats." dans: Journal of diabetes research, Vol. 2016, pp. 9726503, (2016) (PubMed).

Martínez-Vega, Garrido, Partearroyo, Cediel, Zeisel, Martínez-Álvarez, Varela-Moreiras, Varela-Nieto, Pajares: "Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 2, pp. 418-32, (2015) (PubMed).

Lee, Feliers, Mariappan, Sataranatarajan, Choudhury, Gorin, Kasinath: "Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes." dans: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12014-26, (2015) (PubMed).

Synonymes et noms alternatifs relatifs à CBS

cystathionine-beta-synthase L homeolog (cbs.L), cystathionine-beta-synthase (cbs), cystathionine beta-synthase (Cbs), cystathionine-beta-synthase (CBS), cystathionine beta-synthase (CNA06170), cystathionine beta-synthase (Tb11.02.5400), cystathionine beta-synthase CBS (cbs), cystathionine beta-synthase (cbs), cystathionine beta-synthase (cysB), cystathionine beta-synthase (LOC100635325), cystathionine beta synthase (Cbs), cystathionine-beta-synthase S homeolog (cbs.S), cystathionine-beta-synthase b (cbsb), AI047524, AI303044, cb442, CBS, cbs, DDBDRAFT_0189727, DDBDRAFT_0191292, DDB_0189727, DDB_0191292, GB12529, hip4, HIP4, wu:fb37g05, wu:fm61c07, wu:fq06c06, zgc:113704

Protein level used designations for CBS

  • cystathionine-beta-synthase
  • cystathionine beta-synthase
  • cystathionine beta-synthase CBS
  • beta-thionase
  • hemoprotein H-450
  • serine sulfhydrase
  • methylcysteine synthase
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