CBX4 Produits
(Chromobox Homolog 4 (CBX4))
Catégories
E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones\; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
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Catégories CBX4 en vedette
CBX4 Anticorps
High quality antibodies with extensive validation data.
CBX4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CBX4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (6)
N° du produit
ABIN5542423
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7150950
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
- (2)
N° du produit
ABIN389086
Quantité
400 μL
Fiche technique
Fiche technique
CBX4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6209563
Quantité
96 tests
Fiche technique
Fiche technique
CBX4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348212
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3091174
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3131894
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits CBX4
: "HIF-1α SUMOylation affects the stability and transcriptional activity of HIF-1α in human lens epithelial cells." dans: Graefe's archive for clinical and experimental ophthalmology, Vol. 253, Issue 8, pp. 1279-90, (2015) (PubMed).: "Oxidative stress-induced p53 activity is enhanced by a redox-sensitive TP53INP1 SUMOylation." dans: Cell death and differentiation, Vol. 21, Issue 7, pp. 1107-18, (2014) (PubMed).
: "Contribution of CBX4 to cumulus oophorus cell phenotype in mice and attendant effects in cumulus cell cloned embryos." dans: Physiological genomics, Vol. 46, Issue 2, pp. 66-80, (2014) (PubMed).
: "CBX4-mediated SUMO modification regulates BMI1 recruitment at sites of DNA damage." dans: Nucleic acids research, Vol. 40, Issue 12, pp. 5497-510, (2012) (PubMed).
: "Human Polycomb protein 2 promotes ?-synuclein aggregate formation through covalent SUMOylation." dans: Brain research, Vol. 1381, pp. 78-89, (2011) (PubMed).
: "The SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motif." dans: Molecular and cellular biology, Vol. 30, Issue 9, pp. 2193-205, (2010) (PubMed).
: "Different polycomb group CBX family proteins associate with distinct regions of chromatin using nonhomologous protein sequences." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 43, pp. 16572-7, (2008) (PubMed).
: "Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 44, pp. 16272-7, (2006) (PubMed).
: "The polycomb protein Pc2 is a SUMO E3." dans: Cell, Vol. 113, Issue 1, pp. 127-37, (2003) (PubMed).
Synonymes et noms alternatifs relatifs à CBX4
chromobox 4 (CBX4), chromobox 4 (Cbx4), chromobox 4 S homeolog (cbx4.S), chromobox homolog 4 (CBX4), chromobox homolog 4 (Pc class homolog, Drosophila) (cbx4), cbx4-a, im:6911625, MPc2, NBP16, PC2, XPolycomb, zgc:158588Protein level used designations for CBX4
- chromobox homolog 4
- E3 SUMO-protein ligase CBX4
- chromobox protein homolog 4
- polycomb 2 homolog
- NS5ATP1-binding protein 16
- Pc class 2 homolog
- chromobox homolog 4 (Pc class homolog, Drosophila)
- chromobox homolog 4 (Pc class homolog)
- chromobox homolog 4 (Polycomb)
- chromobox protein (CHCB3)
- chromobox-like protein 4
- polycomb 2
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