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CD70 Produits

(CD70 Molecule (CD70))

Catégories

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008].

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Catégories CD70 en vedette

CD70 Anticorps

High quality antibodies with extensive validation data.

CD70 Kits ELISA

Reliable ELISA kits for a wide range of species.

CD70 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CD70 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (6)
N° du produit ABIN3022743
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application FACS
Validations
  • (3)
  • (2)
N° du produit ABIN2749184
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application FACS
Validations
  • (4)
  • (2)
N° du produit ABIN2749173
Quantité 100 tests
Fiche technique Fiche technique

CD70 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6973491
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954532
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1889449
Quantité 96 tests
Fiche technique Fiche technique

CD70 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN7274227
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
N° du produit ABIN6961112
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (3)
N° du produit ABIN7274243
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CD70

Izawa, Martin, Soudais, Bruneau, Boutboul, Rodriguez, Lenoir, Hislop, Besson, Touzot, Picard, Callebaut, de Villartay, Moshous, Fischer, Latour: "Inherited CD70 deficiency in humans reveals a critical role for the CD70-CD27 pathway in immunity to Epstein-Barr virus infection." dans: The Journal of experimental medicine, Vol. 214, Issue 1, pp. 73-89, (2017) (PubMed).

Mazor, Hansen, Yang, Chowdhury, Wang, Stephens, Wu, DallAcqua: "Insights into the molecular basis of a bispecific antibody's target selectivity." dans: mAbs, Vol. 7, Issue 3, pp. 461-9, (2015) (PubMed).

Trebing, El-Mesery, Schäfer, Weisenberger, Siegmund, Silence, Wajant: "CD70-restricted specific activation of TRAILR1 or TRAILR2 using scFv-targeted TRAIL mutants." dans: Cell death & disease, Vol. 5, pp. e1035, (2014) (PubMed).

Hashimoto-Okada, Kitawaki, Kadowaki, Iwata, Morimoto, Hori, Uchiyama: "The CD70-CD27 interaction during the stimulation with dendritic cells promotes naive CD4(+) T cells to develop into T cells producing a broad array of immunostimulatory cytokines in humans." dans: International immunology, Vol. 21, Issue 8, pp. 891-904, (2009) (PubMed).

Kaufmann, Amariglio, Rosenthal, Hirsch, Many, Rechavi: "Proliferation response of leukemic cells to CD70 ligation oscillates with recurrent remission and relapse in a low-grade lymphoma." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 175, Issue 10, pp. 6940-7, (2005) (PubMed).

Baki, Marambaud, Efthimiopoulos, Georgakopoulos, Wen, Cui, Shioi, Koo, Ozawa, Friedrich, Robakis: "Presenilin-1 binds cytoplasmic epithelial cadherin, inhibits cadherin/p120 association, and regulates stability and function of the cadherin/catenin adhesion complex." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 5, pp. 2381-6, (2001) (PubMed).

Israel, Pickles, Segal, Gerard, Kenney: "Enhancement of adenovirus vector entry into CD70-positive B-cell Lines by using a bispecific CD70-adenovirus fiber antibody." dans: Journal of virology, Vol. 75, Issue 11, pp. 5215-21, (2001) (PubMed).

MacLaren, Clark, Gillespie: "v-Jun sensitizes cells to apoptosis by a mechanism involving mitochondrial cytochrome C release." dans: Oncogene, Vol. 19, Issue 51, pp. 5906-18, (2000) (PubMed).

Akiba, Miyahira, Atsuta, Takeda, Nohara, Futagawa, Matsuda, Aoki, Yagita, Okumura: "Critical contribution of OX40 ligand to T helper cell type 2 differentiation in experimental leishmaniasis." dans: The Journal of experimental medicine, Vol. 191, Issue 2, pp. 375-80, (2000) (PubMed).

Takeda, Oshima, Hayakawa, Akiba, Atsuta, Kobata, Kobayashi, Ito, Yagita, Okumura: "CD27-mediated activation of murine NK cells." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 164, Issue 4, pp. 1741-5, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à CD70

CD70 antigen (Cd70), CD70 molecule (CD70), Cd70 molecule (Cd70), Cd27l, CD27L, CD27LG, Tnfsf7, TNFSF7

Protein level used designations for CD70

  • CD27 ligand
  • CD27-L
  • Ki-24 antigen
  • tumor necrosis factor (ligand) superfamily, member 7
  • tumor necrosis factor ligand superfamily member 7
  • CD70 antigen
  • surface antigen CD70
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