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CD8B Produits

(CD8b Molecule (CD8B))

Catégories

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 beta chain isoforms. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified. [provided by RefSeq, May 2010].

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Catégories CD8B en vedette

CD8B Anticorps

High quality antibodies with extensive validation data.

CD8B Kits ELISA

Reliable ELISA kits for a wide range of species.

CD8B Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CD8B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application IHC, IF
Validations
  • (4)
N° du produit ABIN7073405
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application FACS, WB, IP, IHC (fro)
Validations
  • (9)
  • (2)
N° du produit ABIN609653
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Rat
Application FACS
Validations
  • (8)
  • (2)
N° du produit ABIN2749076
Quantité 0.1 mg
Fiche technique Fiche technique

CD8B recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6954540
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6730451
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1160710
Quantité 96 tests
Fiche technique Fiche technique

CD8B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1348728
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1348730
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Human Cells
Validations
  • (1)
N° du produit ABIN7319847
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CD8B

Martinez, Marteinsdottir, Josefsson, Sydsjö, Theodorsson, Rodriguez-Martinez: "Prenatal stress, anxiety and depression alter transcripts, proteins and pathways associated with immune responses at the maternal-fetal interface†." dans: Biology of reproduction, Vol. 106, Issue 3, pp. 449-462, (2022) (PubMed).

Lacharme-Lora, Chaloner, Gilroy, Humphrey, Gibbs, Jopson, Wright, Reid, Ketley, Humphrey, Williams, Rushton, Wigley: "B lymphocytes play a limited role in clearance of Campylobacter jejuni from the chicken intestinal tract." dans: Scientific reports, Vol. 7, pp. 45090, (2018) (PubMed).

Vermeulen, Devriendt, Olyslaegers, Dedeurwaerder, Desmarets, Favoreel, Dewerchin, Nauwynck: "Suppression of NK cells and regulatory T lymphocytes in cats naturally infected with feline infectious peritonitis virus." dans: Veterinary microbiology, Vol. 164, Issue 1-2, pp. 46-59, (2013) (PubMed).

Heigele, Schindler, Gnanadurai, Leonard, Collins, Kirchhoff: "Down-modulation of CD8αβ is a fundamental activity of primate lentiviral Nef proteins." dans: Journal of virology, Vol. 86, Issue 1, pp. 36-48, (2012) (PubMed).

Vermeulen, Gleich, Dedeurwaerder, Olyslaegers, Desmarets, Dewerchin, Nauwynck: "In vitro assessment of the feline cell-mediated immune response against feline panleukopeniavirus, calicivirus and felid herpesvirus 1 using 5-bromo-2'-deoxyuridine labeling." dans: Veterinary immunology and immunopathology, Vol. 146, Issue 2, pp. 177-84, (2012) (PubMed).

Vermeulen, Devriendt, Olyslaegers, Dedeurwaerder, Desmarets, Grauwet, Favoreel, Dewerchin, Nauwynck: "Natural killer cells: frequency, phenotype and function in healthy cats." dans: Veterinary immunology and immunopathology, Vol. 150, Issue 1-2, pp. 69-78, (2012) (PubMed).

Dalgaard, Norup, Pedersen, Handberg, Juorgensen, Juul-Madsen: "Flow cytometric assessment of chicken T cell-mediated immune responses after Newcastle disease virus vaccination and challenge." dans: Vaccine, (2010) (PubMed).

Rossi, Del Principe, Rossi, Irno Consalvo, Luciano, Zucchetto, Bulian, Bomben, Dal Bo, Fangazio, Benedetti, Degan, Gaidano, Del Poeta, Gattei: "Prognostic impact of ZAP-70 expression in chronic lymphocytic leukemia: mean fluorescence intensity T/B ratio versus percentage of positive cells." dans: Journal of translational medicine, Vol. 8, pp. 23, (2010) (PubMed).

Vroblova, Vrbacky, Hrudkova, Jankovicova, Schmitzova, Maly, Krejsek, Smolej: "Significant change in ZAP-70 expression during the course of chronic lymphocytic leukemia." dans: European journal of haematology, Vol. 84, Issue 6, pp. 513-7, (2010) (PubMed).

Luckschander, Pfammatter, Sidler, Jakob, Burgener, Moore, Zurbriggen, Corazza, Brunner: "Phenotyping, functional characterization, and developmental changes in canine intestinal intraepithelial lymphocytes." dans: Veterinary research, Vol. 40, Issue 6, pp. 58, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à CD8B

CD8b molecule (Cd8b), CD8b molecule (CD8B), CD8 antigen, beta chain 1 (Cd8b1), Cd8b, CD8B1, Cd8b1, LEU2, Ly-3, Ly-C, LY3, Lyt-3, LYT3, P37

Protein level used designations for CD8B

  • CD8 beta
  • CD8 beta-2
  • T-cell surface glycoprotein CD8 beta chain
  • CD8 antigen beta polypeptide
  • T-cell membrane glycoprotein Ly-3
  • T-cell surface glycoprotein Lyt-3
  • lymphocyte antigen 3
  • CD8 antigen, beta polypeptide 1 (p37)
  • T lymphocyte surface glycoprotein beta chain
  • CD8 antigen 37 kDa chain
  • CD8 antigen beta-chain
  • CD8 antigen, beta chain
  • CD8 antigen, beta-chain
  • OX-8 membrane antigen
  • CD8 beta chain
  • CD8 antigen, beta polypeptide
  • CD8b antigen
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