CDK7 Produits
(Cyclin-Dependent Kinase 7 (CDK7))
Catégories
The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008].
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Catégories CDK7 en vedette
CDK7 Anticorps
High quality antibodies with extensive validation data.
CDK7 Kits ELISA
Reliable ELISA kits for a wide range of species.
CDK7 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CDK7 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF
Validations
- (6)
N° du produit
ABIN3022405
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p), DB
Validations
- (4)
N° du produit
ABIN389541
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, IF
Validations
- (4)
N° du produit
ABIN7259474
Quantité
200 μL
Fiche technique
Fiche technique
CDK7 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966173
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380387
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Pig
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN778532
Quantité
96 tests
Fiche technique
Fiche technique
CDK7 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect cells (Sf21)
Validations
- (2)
N° du produit
ABIN5570487
Quantité
5 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
N° du produit
ABIN5569618
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1348979
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CDK7
: "Androgen suppresses the proliferation of androgen receptor-positive castration-resistant prostate cancer cells via inhibition of Cdk2, CyclinA, and Skp2." dans: PLoS ONE, Vol. 9, Issue 10, pp. e109170, (2014) (PubMed).: "Cross-talk among RNA polymerase II kinases modulates C-terminal domain phosphorylation." dans: The Journal of biological chemistry, Vol. 287, Issue 46, pp. 38755-66, (2012) (PubMed).
: "CDKN1C negatively regulates RNA polymerase II C-terminal domain phosphorylation in an E2F1-dependent manner." dans: The Journal of biological chemistry, Vol. 285, Issue 13, pp. 9813-22, (2010) (PubMed).
: "Cell cycle control of embryonic stem cells." dans: Stem cell reviews, Vol. 1, Issue 2, pp. 131-8, (2006) (PubMed).
: "Adaptation to the ionizing radiation-induced G2 checkpoint occurs in human cells and depends on checkpoint kinase 1 and Polo-like kinase 1 kinases." dans: Cancer research, Vol. 66, Issue 21, pp. 10253-7, (2006) (PubMed).
: "Secrets of a double agent: CDK7 in cell-cycle control and transcription." dans: Journal of cell science, Vol. 118, Issue Pt 22, pp. 5171-80, (2005) (PubMed).
: "The Tat/TAR-dependent phosphorylation of RNA polymerase II C-terminal domain stimulates cotranscriptional capping of HIV-1 mRNA." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, Issue 22, pp. 12666-71, (2003) (PubMed).
: "The cyclin H/cdk7/Mat1 kinase activity is regulated by CK2 phosphorylation of cyclin H." dans: Oncogene, Vol. 21, Issue 33, pp. 5031-7, (2002) (PubMed).
: "Transcription factor TFIIH components enhance the GR coactivator activity but not the cell cycle-arresting activity of the human immunodeficiency virus type-1 protein Vpr." dans: Biochemical and biophysical research communications, Vol. 298, Issue 1, pp. 17-23, (2002) (PubMed).
: "Inhibition of transcription by the trimeric cyclin-dependent kinase 7 complex." dans: The Journal of biological chemistry, Vol. 274, Issue 19, pp. 13162-6, (1999) (PubMed).
Synonymes et noms alternatifs relatifs à CDK7
cyclin dependent kinase 7 (CDK7), cyclin-dependent kinase 7 (Cdk7), Cyclin-dependent kinase 7 (Cdk7), cyclin-dependent kinase 7 L homeolog (cdk7.L), cyclin-dependent kinase 7 (cdk7), cyclin dependent kinase 7 (Cdk7), AI323415, AI528512, C230069N13, CAK1, cak1, CD 7, cdk-7, CDK7, cdk7, CDKN7, Cdkn7, cdkn7, CG3319, Crk4, dCdk7, DmCDK7, DmCdk7, Dmcdk7, Dmel\\CG3319, DmMO15, DmMo15, HCAK, MO15, Mo15, p39MO15, p39mo15, p40MO15, p40[MO15], STK1, stk1, zgc:85821Protein level used designations for CDK7
- 39 KDa protein kinase
- CAK
- CDK-activating kinase 1
- TFIIH basal transcription factor complex kinase subunit
- cell division protein kinase 7
- cyclin-dependent kinase 7 (MO15 homolog, Xenopus laevis, cdk-activating kinase)
- homolog of Xenopus MO15 Cdk-activating kinase
- kinase subunit of CAK
- p39 Mo15
- protein kinase
- serine/threonine kinase stk1
- serine/threonine protein kinase 1
- serine/threonine protein kinase MO15
- serine/threonine-protein kinase 1
- 39 kDa protein kinase
- CDK-activating kinase
- CR4 protein kinase
- CRK4 PK (CDC2-related-kinase-4 protein kinase)
- P39 Mo15
- cyclin-dependent kinase 7 (homolog of Xenopus MO15 cdk-activating kinase)
- protein-tyrosine kinase MPK-7
- 39 protein kinase
- cyclin-dependent kinase 7 (MO15 homolog Xenopus laevis cdk-activating kinase)
- CG3319-PA
- Cdk7-PA
- Mo15
- 40 kDa protein kinase
- CDC2/CDK2,4-activating kinase
- P40 MO15
- cyclin-dependent kinase 7 (MO15, cdk-activating kinase)
- cell division protein kinase 7-like protein
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