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CDKL5 Produits

(Cyclin-Dependent Kinase-Like 5 (CDKL5))

Catégories

This gene is a member of Ser/Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008].

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Catégories CDKL5 en vedette

CDKL5 Anticorps

High quality antibodies with extensive validation data.

CDKL5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CDKL5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (1)
  • (2)
N° du produit ABIN543776
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
N° du produit ABIN391362
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (2)
N° du produit ABIN563054
Quantité 100 μg
Fiche technique Fiche technique

CDKL5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1349001
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3090896
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3122168
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits CDKL5

Ricciardi, Ungaro, Hambrock, Rademacher, Stefanelli, Brambilla, Sessa, Magagnotti, Bachi, Giarda, Verpelli, Kilstrup-Nielsen, Sala, Kalscheuer, Broccoli: "CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons." dans: Nature cell biology, Vol. 14, Issue 9, pp. 911-23, (2012) (PubMed).

Kalscheuer, Tao, Donnelly, Hollway, Schwinger, Kübart, Menzel, Hoeltzenbein, Tommerup, Eyre, Harbord, Haan, Sutherland, Ropers, Gécz: "Disruption of the serine/threonine kinase 9 gene causes severe X-linked infantile spasms and mental retardation." dans: American journal of human genetics, Vol. 72, Issue 6, pp. 1401-11, (2003) (PubMed).

Barbara, Wrana, Letarte: "Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily." dans: The Journal of biological chemistry, Vol. 274, Issue 2, pp. 584-94, (1999) (PubMed).

Li, Sorensen, Brooke, Urness, Davis, Taylor, Boak, Wendel: "Defective angiogenesis in mice lacking endoglin." dans: Science (New York, N.Y.), Vol. 284, Issue 5419, pp. 1534-7, (1999) (PubMed).

Bellón, Corbí, Lastres, Calés, Cebrián, Vera, Cheifetz, Massague, Letarte, Bernabéu: "Identification and expression of two forms of the human transforming growth factor-beta-binding protein endoglin with distinct cytoplasmic regions." dans: European journal of immunology, Vol. 23, Issue 9, pp. 2340-5, (1993) (PubMed).

Gougos, Letarte: "Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells." dans: The Journal of biological chemistry, Vol. 265, Issue 15, pp. 8361-4, (1990) (PubMed).

Synonymes et noms alternatifs relatifs à CDKL5

cyclin dependent kinase like 5 (CDKL5), cyclin dependent kinase like 5 (cdkl5), cyclin-dependent kinase-like 5 (Cdkl5), BC038161, EIEE2, issx, ISSX, stk9, STK9, Stk9

Protein level used designations for CDKL5

  • cyclin-dependent kinase-like 5
  • cyclin-dependent kinase-like 5-like
  • cyclin dependent kinase 5 transcript
  • serine/threonine kinase 9
  • serine/threonine-protein kinase 9
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