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CHMP4B Produits

(Charged Multivesicular Body Protein 4B (CHMP4B))

Catégories

This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.[provided by RefSeq, Oct 2009].

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Catégories CHMP4B en vedette

CHMP4B Anticorps

High quality antibodies with extensive validation data.

CHMP4B Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

CHMP4B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Rat
Application ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro)
Validations
  • (4)
N° du produit ABIN872575
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN653481
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IF
Validations
  • (4)
N° du produit ABIN6138549
Quantité 100 μL
Fiche technique Fiche technique

CHMP4B recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6228058
Quantité 96 tests
Fiche technique Fiche technique

CHMP4B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3091542
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3137111
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
N° du produit ABIN2713984
Quantité 20 μg
Fiche technique Fiche technique

Dernières publications sur nos produits CHMP4B

Hu, Jiang, Chen, Wei, Zhang, Zhao, Ni, Lu, Wan: "High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma." dans: Tumour biology, Vol. 36, Issue 4, pp. 2569-81, (2015) (PubMed).

Bodon, Chassefeyre, Pernet-Gallay, Martinelli, Effantin, Hulsik, Belly, Goldberg, Chatellard-Causse, Blot, Schoehn, Weissenhorn, Sadoul: "Charged multivesicular body protein 2B (CHMP2B) of the endosomal sorting complex required for transport-III (ESCRT-III) polymerizes into helical structures deforming the plasma membrane." dans: The Journal of biological chemistry, Vol. 286, Issue 46, pp. 40276-86, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à CHMP4B

charged multivesicular body protein 4B (CHMP4B), charged multivesicular body protein 4B (Chmp4b), charged multivesicular body protein 4Ba (chmp4ba), charged multivesicular body protein 4B L homeolog (chmp4b.L), charged multivesicular body protein 4Bb (chmp4bb), 2010012F05Rik, C20orf178, c20orf178, C76846, CHMP4A, CHMP4b, chmp4b, chmp4b.S, CHMP4c, CTPP3, CTRCT31, dJ553F4.4, RGD1309846, RGD1565889, Shax1, SNF7, SNF7-2, Snf7-2, Vps32-2, VPS32B, wu:fc96b02, zgc:55566

Protein level used designations for CHMP4B

  • SNF7 homolog associated with Alix 1
  • Snf7 homologue associated with Alix 1
  • charged multivesicular body protein 4b
  • chromatin modifying protein 4B
  • chromatin-modifying protein 4b
  • hSnf7-2
  • hVps32-2
  • vacuolar protein sorting-associated protein 32-2
  • vacuolar protein-sorting-associated protein 32-2
  • CHMP4b
  • Chromatin-modifying protein 4b
  • charged multivesicular body protein 4B S homeolog
  • CHMP4c
  • Chromatin-modifying protein 4c
  • charged multivesicular body protein 4B
  • charged multivesicular body protein 4c
  • chromatin-modifying protein 4c
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