CHMP4B Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2713984

Détail du produit

Antigène: CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CHMP4B protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human CHMP4B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CHMP4B (Charged Multivesicular Body Protein 4B (CHMP4B))

Autre désignation: Chmp4b (CHMP4B Produits)

Synonymes: C20orf178 Protein, CHMP4A Protein, CTPP3 Protein, CTRCT31 Protein, SNF7 Protein, SNF7-2 Protein, Shax1 Protein, VPS32B Protein, Vps32-2 Protein, dJ553F4.4 Protein, 2010012F05Rik Protein, C76846 Protein, Snf7-2 Protein, RGD1309846 Protein, RGD1565889 Protein, CHMP4b Protein, chmp4b Protein, chmp4b.S Protein, CHMP4c Protein, c20orf178 Protein, wu:fc96b02 Protein, zgc:55566 Protein, charged multivesicular body protein 4B Protein, charged multivesicular body protein 4Ba Protein, charged multivesicular body protein 4B L homeolog Protein, charged multivesicular body protein 4Bb Protein, CHMP4B Protein, Chmp4b Protein, chmp4ba Protein, chmp4b.L Protein, chmp4bb Protein

Sujet: This gene encodes a member of the chromatin-modifying protein/charged multivesicular body protein (CHMP) protein family. The protein is part of the endosomal sorting complex required for transport (ESCRT) complex III (ESCRT-III), which functions in the sorting of endocytosed cell-surface receptors into multivesicular endosomes. The ESCRT machinery also functions in the final abscisson stage of cytokinesis and in the budding of enveloped viruses such as HIV-1. The three proteins of the CHMP4 subfamily interact with programmed cell death 6 interacting protein (PDCD6IP, also known as ALIX), which also functions in the ESCRT pathway. The CHMP4 proteins assemble into membrane-attached 5-nm filaments that form circular scaffolds and promote or stabilize outward budding. These polymers are proposed to help generate the luminal vesicles of multivesicular bodies. Mutations in this gene result in autosomal dominant posterior polar cataracts.[provided by RefSeq, Oct 2009].

Poids moléculaire: 24.8 kDa

NCBI Accession: NP_789782