Crk Produits
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian) (CRK))
Catégories
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008].
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Catégories Crk en vedette
Crk Anticorps
High quality antibodies with extensive validation data.
Crk Kits ELISA
Reliable ELISA kits for a wide range of species.
Crk Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
Crk recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (2)
- (7)
N° du produit
ABIN969062
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, PLA
Validations
- (4)
N° du produit
ABIN514602
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human, Monkey, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (4)
N° du produit
ABIN6256674
Quantité
100 μL
Fiche technique
Fiche technique
Crk recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6971097
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380115
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN5691928
Quantité
2 x 96 tests
Fiche technique
Fiche technique
Crk recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7125676
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350363
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350365
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits Crk
: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).: "Identification and characterization of proteins isolated from microvesicles derived from human lung cancer pleural effusions." dans: Proteomics, Vol. 13, Issue 14, pp. 2125-34, (2013) (PubMed).
: "Adaptor protein Crk induces Src-dependent activation of p38 MAPK in regulation of synovial sarcoma cell proliferation." dans: Molecular cancer research : MCR, Vol. 7, Issue 9, pp. 1582-92, (2009) (PubMed).
: "[Biological roles of signaling adaptor protein CRK]." dans: Seikagaku. The Journal of Japanese Biochemical Society, Vol. 81, Issue 5, pp. 361-76, (2009) (PubMed).
: "Avian and 1918 Spanish influenza a virus NS1 proteins bind to Crk/CrkL Src homology 3 domains to activate host cell signaling." dans: The Journal of biological chemistry, Vol. 283, Issue 9, pp. 5719-27, (2008) (PubMed).
: "Signaling adaptor protein Crk is indispensable for malignant feature of glioblastoma cell line KMG4." dans: Biochemical and biophysical research communications, Vol. 362, Issue 4, pp. 976-81, (2007) (PubMed).
: "The carboxyl-terminal SH3 domain of the mammalian adaptor CrkII promotes internalization of Listeria monocytogenes through activation of host phosphoinositide 3-kinase." dans: Cellular microbiology, Vol. 9, Issue 10, pp. 2497-516, (2007) (PubMed).
: "RET/papillary thyroid carcinoma oncogenic signaling through the Rap1 small GTPase." dans: Cancer research, Vol. 67, Issue 1, pp. 381-90, (2007) (PubMed).
: "Nck and Crk mediate distinct VEGF-induced signaling pathways that serve overlapping functions in focal adhesion turnover and integrin activation." dans: Experimental cell research, Vol. 295, Issue 1, pp. 258-68, (2004) (PubMed).
: "Cortactin and Crk cooperate to trigger actin polymerization during Shigella invasion of epithelial cells." dans: The Journal of cell biology, Vol. 166, Issue 2, pp. 225-35, (2004) (PubMed).
Synonymes et noms alternatifs relatifs à Crk
Crk oncogene (Crk), v-crk avian sarcoma virus CT10 oncogene homolog (crk), CRK proto-oncogene, adaptor protein (CRK), CRK proto-oncogene, adaptor protein (Crk), v-crk avian sarcoma virus CT10 oncogene homolog L homeolog (crk.L), v-crk sarcoma virus CT10 oncogene homolog (CRK), v-crk avian sarcoma virus CT10 oncogene homolog (Crk), c-Crk, CG1587, CRK, crk, Crk-I, Crk-II, Crk-III, crk2, Crk3, CRKII, crkII, CrkIII, Crko, D-CRK, D-Crk, DCrk, Dcrk, dCRK, dCrk, Dmel\\CG1587, fb34h10, fc05a01, fi19g05, p38, P38C-CRK, v-crk, wu:fb34h10, wu:fc05a01, wu:fc54a04, wu:fi19g05, zgc:100936Protein level used designations for Crk
- CG1587-PA
- CG1587-PB
- CG1587-PC
- CG1587-PD
- CG1587-PE
- CG1587-PF
- Crk-PA
- Crk-PB
- Crk-PC
- Crk-PD
- Crk-PE
- Crk-PF
- adapter molecule crk
- v-crk sarcoma virus CT10 oncogene homolog (avian)
- proto-oncogene c-Crk
- avian sarcoma virus CT10 (v-crk) oncogene homolog
- p38
- proto-oncogene C-crk
- v-crk sarcoma virus CT10 oncogene homolog
- SH2/SH3 adaptor Crk2
- SH2/SH3 adaptor crk
- CT-10 related kinase 3
- proto-oncogene c-crk
- v-crk sarcoma virus CT10 oncogene-like protein
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