CrkL Produits
(V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
Catégories
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.[provided by RefSeq, Jan 2009].
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Catégories CrkL en vedette
CrkL Anticorps
High quality antibodies with extensive validation data.
CrkL Kits ELISA
Reliable ELISA kits for a wide range of species.
CrkL Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
CrkL recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IF, PLA
Validations
- (1)
- (7)
N° du produit
ABIN514605
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, PLA, RNAi
Validations
- (2)
- (8)
N° du produit
ABIN514606
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, FACS
Validations
- (1)
- (3)
N° du produit
ABIN969064
Quantité
100 μL
Fiche technique
Fiche technique
CrkL recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960414
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6960415
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380116
Quantité
2 x 96 tests
Fiche technique
Fiche technique
CrkL recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN667314
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1350367
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7408720
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits CrkL
: "Increased Soluble CrkL in Serum of Breast Cancer Patients Is Associated with Advanced Disease." dans: Cancers, Vol. 11, Issue 7, (2019) (PubMed).: "CRKL promotes lung cancer cell invasion through ERK-MMP9 pathway." dans: Molecular carcinogenesis, Vol. 54 Suppl 1, pp. E35-44, (2015) (PubMed).
: "CRKL protein overexpression enhances cell proliferation and invasion in pancreatic cancer." dans: Tumour biology, Vol. 36, Issue 2, pp. 1015-22, (2015) (PubMed).
: "Clinical significance and biological roles of CRKL in human bladder carcinoma." dans: Tumour biology, Vol. 35, Issue 5, pp. 4101-6, (2014) (PubMed).
: "Analysis of protein-protein interactions in cross-talk pathways reveals CRKL protein as a novel prognostic marker in hepatocellular carcinoma." dans: Molecular & cellular proteomics : MCP, Vol. 12, Issue 5, pp. 1335-49, (2013) (PubMed).
: "Escherichia coli virulence protein NleH1 interaction with the v-Crk sarcoma virus CT10 oncogene-like protein (CRKL) governs NleH1 inhibition of the ribosomal protein S3 (RPS3)/nuclear factor κB ..." dans: The Journal of biological chemistry, Vol. 288, Issue 48, pp. 34567-74, (2013) (PubMed).
: "Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer." dans: Oncogene, Vol. 29, Issue 10, pp. 1421-30, (2010) (PubMed).
: "Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop." dans: Molecular and cellular biology, Vol. 29, Issue 11, pp. 3076-87, (2009) (PubMed).
: "PI3K links NKG2D signaling to a CrkL pathway involved in natural killer cell adhesion, polarity, and granule secretion." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 11, pp. 6933-42, (2009) (PubMed).
: "Active (p)CrkL is overexpressed in human malignancies: potential role as a surrogate parameter for therapeutic tyrosine kinase inhibition." dans: Oncology reports, Vol. 15, Issue 2, pp. 353-9, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à CrkL
CRK like proto-oncogene, adaptor protein (CRKL), v-crk avian sarcoma virus CT10 oncogene homolog-like (crkl), v-crk avian sarcoma virus CT10 oncogene homolog-like (Crkl), 1110025F07Rik, AA589403, AI325100, CRKL, Crkol, wu:fa55g05, wu:fj60e01, zgc:63469Protein level used designations for CrkL
- v-crk sarcoma virus CT10 oncogene homolog (avian)-like
- crk-like protein
- v-crk sarcoma virus CT10 oncogene homolog-like
- v-crk avian sarcoma virus CT10 oncogene homolog-like
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