DCC Produits
(Deleted in Colorectal Carcinoma (DCC))
Catégories
This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009].
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Catégories DCC en vedette
DCC Anticorps
High quality antibodies with extensive validation data.
DCC Kits ELISA
Reliable ELISA kits for a wide range of species.
DCC Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DCC recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC (f)
Validations
- (6)
- (3)
N° du produit
ABIN967443
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (4)
N° du produit
ABIN2782671
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IF, ICC
Validations
- (2)
N° du produit
ABIN6257126
Quantité
100 μL
Fiche technique
Fiche technique
DCC recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966310
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6730147
Quantité
96 tests
Fiche technique
Fiche technique
DCC recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7122626
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3078676
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3120923
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits DCC
: "Progesterone down-regulates SLIT/ROBO expression in mouse corpus luteum." dans: Acta histochemica, Vol. 119, Issue 7, pp. 740-746, (2017) (PubMed).: "Coexpression of high-voltage-activated ion channels Kv3.4 and Cav1.2 in pioneer axons during pathfinding in the developing rat forebrain." dans: The Journal of comparative neurology, Vol. 520, Issue 16, pp. 3650-72, (2012) (PubMed).
: "The DCC protein and prognosis in colorectal cancer." dans: The New England journal of medicine, Vol. 335, Issue 23, pp. 1727-32, (1996) (PubMed).
: "Expression and alternative splicing of the deleted in colorectal cancer (DCC) gene in normal and malignant tissues." dans: Cancer research, Vol. 54, Issue 16, pp. 4493-501, (1994) (PubMed).
: "Identification of a chromosome 18q gene that is altered in colorectal cancers." dans: Science (New York, N.Y.), Vol. 247, Issue 4938, pp. 49-56, (1990) (PubMed).
: "Genetic alterations during colorectal-tumor development." dans: The New England journal of medicine, Vol. 319, Issue 9, pp. 525-32, (1988) (PubMed).
: "Clonal analysis of human colorectal tumors." dans: Science (New York, N.Y.), Vol. 238, Issue 4824, pp. 193-7, (1987) (PubMed).
Synonymes et noms alternatifs relatifs à DCC
DCC netrin 1 receptor (DCC), DCC netrin 1 receptor (dcc), deleted in colorectal carcinoma (Dcc), deleted in colorectal carcinoma (dcc), DCC netrin 1 receptor (Dcc), netrin receptor DCC (LOC100712666), C030036D22Rik, CRC18, CRCR1, DCC, Dcc, dcca-A, IGDCC1, Igdcc1, MRMV1, xdcc, XDCCa, zdccProtein level used designations for DCC
- colorectal cancer suppressor
- colorectal tumor suppressor
- deleted in colorectal cancer protein
- immunoglobulin superfamily DCC subclass member 1
- immunoglobulin superfamily, DCC subclass, member 1
- netrin receptor DCC
- tumor suppressor protein DCC
- deleted in colorectal carcinoma
- deleted in colorectal cancer
- deleted in colorectal cancer tumor suppressor
- netrin receptor DCC-like
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