DIO2 Produits
(Deiodinase, Iodothyronine, Type II (DIO2))
Catégories
The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories DIO2 en vedette
DIO2 Anticorps
High quality antibodies with extensive validation data.
DIO2 Kits ELISA
Reliable ELISA kits for a wide range of species.
DIO2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DIO2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC (p), FACS
Validations
- (5)
N° du produit
ABIN652664
Quantité
400 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
ELISA, IHC, FACS, IF
Validations
- (1)
- (3)
N° du produit
ABIN190862
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (2)
N° du produit
ABIN7173972
Quantité
100 μg
Fiche technique
Fiche technique
DIO2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
N° du produit
ABIN6966307
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955327
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955328
Quantité
96 tests
Fiche technique
Fiche technique
DIO2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351608
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
N° du produit
ABIN3120328
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7413544
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DIO2
: "Prolonged inorganic arsenic exposure via drinking water impairs brown adipose tissue function in mice." dans: The Science of the total environment, Vol. 668, pp. 310-317, (2019) (PubMed).: "Multipotent stem cell factor UGS148 is a marker for tanycytes in the adult hypothalamus." dans: Molecular and cellular neurosciences, Vol. 65, pp. 21-30, (2015) (PubMed).
: "Reprogrammed Functional Brown Adipocytes Ameliorate Insulin Resistance and Dyslipidemia in Diet-Induced Obesity and Type 2 Diabetes." dans: Stem cell reports, Vol. 5, Issue 4, pp. 569-81, (2015) (PubMed).
: "Treatment with thyroxine restores myelination and clinical recovery after intraventricular hemorrhage." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 33, Issue 44, pp. 17232-46, (2013) (PubMed).
: "Contributions of HIV infection in the hypothalamus and substance abuse/use to HPT dysregulation." dans: Psychoneuroendocrinology, Vol. 36, Issue 5, pp. 710-9, (2011) (PubMed).
: "Ala92 type 2 deiodinase allele increases risk for the development of hypertension." dans: Hypertension, Vol. 49, Issue 3, pp. 461-6, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à DIO2
iodothyronine deiodinase 2 (DIO2), deiodinase, iodothyronine, type II (Dio2), iodothyronine deiodinase 2 (dio2), deiodinase, iodothyronine, type II (dio2), deiodinase, iodothyronine, type 2 L homeolog (dio2.L), deiodinase, iodothyronine, type 2 (dio2), iodothyronine deiodinase 2 (Dio2), type II iodothyronine deiodinase (LOC100861220), 5DII, 5dii, AI324267, cb684, D2, Deio2, DIO2, dio2-A, DIOII, SelY, sely, TXDI2, txdi2Protein level used designations for DIO2
- thyroxine deiodinase, type II
- type 2 DI
- type 2 iodothyronine deiodinase
- type II iodothyronine deiodinase
- type-II 5'-deiodinase
- type-II 5'deiodinase
- iodothyronine type II deiodinase
- type-II 5' deiodinase
- deiodinase, iodothyronine, type 2
- D2
- 5DII
- DIOII
- deiodinase, iodothyronine, type II
- deiodinase 2
- type 2 deiodinase
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