DOT1L Produits
(DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L))
Catégories
The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011].
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Catégories DOT1L en vedette
DOT1L Anticorps
High quality antibodies with extensive validation data.
DOT1L Kits ELISA
Reliable ELISA kits for a wide range of species.
DOT1L Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
DOT1L recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (1)
- (4)
N° du produit
ABIN566567
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
N° du produit
ABIN7155530
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
IHC (p)
Validations
- (2)
- (1)
N° du produit
ABIN6243177
Quantité
400 μL
Fiche technique
Fiche technique
DOT1L recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955450
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955451
Quantité
96 tests
Fiche technique
Fiche technique
DOT1L recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1351915
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (2)
N° du produit
ABIN2669718
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7317542
Quantité
50 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits DOT1L
: "miR-133b suppresses colorectal cancer cell stemness and chemoresistance by targeting methyltransferase DOT1L." dans: Experimental cell research, Vol. 385, Issue 1, pp. 111597, (2019) (PubMed).: "An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy." dans: Oncotarget, Vol. 9, Issue 27, pp. 19079-19099, (2018) (PubMed).
: "2D-DIGE proteomic analysis of vastus lateralis from COPD patients with low and normal fat free mass index and healthy controls." dans: Respiratory research, Vol. 18, Issue 1, pp. 81, (2018) (PubMed).
: "Copy-number variation and protein expression of DOT1L in pancreatic adenocarcinoma as a potential drug target." dans: Molecular and clinical oncology, Vol. 6, Issue 5, pp. 639-642, (2017) (PubMed).
: "Functional interdependence of BRD4 and DOT1L in MLL leukemia. ..." dans: Nature structural & molecular biology, Vol. 23, Issue 7, pp. 673-81, (2016) (PubMed).
: "Incidence of methylated histones H3K4 and H3K79 in cat germinal vesicles is regulated by specific nuclear factors at the acquisition of developmental competence during the folliculogenesis." dans: Journal of assisted reproduction and genetics, Vol. 33, Issue 6, pp. 783-94, (2016) (PubMed).
: "Histone methyltransferase DOT1L drives recovery of gene expression after a genotoxic attack." dans: PLoS genetics, Vol. 9, Issue 7, pp. e1003611, (2013) (PubMed).
: "Polycomb eviction as a new distant enhancer function." dans: Genes & development, Vol. 25, Issue 15, pp. 1583-8, (2011) (PubMed).
: "A novel disrupter of telomere silencing 1-like (DOT1L) interaction is required for signal transducer and activator of transcription 1 (STAT1)-activated gene expression." dans: The Journal of biological chemistry, Vol. 286, Issue 48, pp. 41195-204, (2011) (PubMed).
: "DOT1L regulates dystrophin expression and is critical for cardiac function." dans: Genes & development, Vol. 25, Issue 3, pp. 263-74, (2011) (PubMed).
Synonymes et noms alternatifs relatifs à DOT1L
histone-lysine N-methyltransferase, H3 lysine-79 specific (LOC100116648), DOT1 like histone lysine methyltransferase (DOT1L), histone methyltransferase (DOT1), DOT1 like histone lysine methyltransferase (Dot1l), DOT1-like, histone H3 methyltransferase (S. cerevisiae) (Dot1l), A630076O07, AW907654, DOT1, Dot1, DOT1L, KMT4, mDot1, NV11307Protein level used designations for DOT1L
- histone-lysine N-methyltransferase, H3 lysine-79 specific
- DOT1-like, histone H3 methyltransferase (S. cerevisiae)
- histone-lysine N-methyltransferase, H3 lysine-79 specific-like
- possible nucleosomal histone methylase
- DOT1-like protein
- DOT1-like, histone H3 methyltransferase
- H3-K79-HMTase
- histone H3-K79 methyltransferase
- histone methyltransferase DOT1L
- lysine N-methyltransferase 4
- DOT1-like histone H3 methyltransferase
- histone H3 methyltransferase DOT1
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