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DUOX1 Produits

(Dual Oxidase 1 (DUOX1))
The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq, Jul 2012].

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Catégories DUOX1 en vedette

DUOX1 Anticorps

High quality antibodies with extensive validation data.

DUOX1 Kits ELISA

Reliable ELISA kits for a wide range of species.

DUOX1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

DUOX1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7150689
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application ELISA, WB, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
Validations
  • (1)
N° du produit ABIN1386159
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application ELISA, WB
Validations
  • (1)
N° du produit ABIN526989
Quantité 50 μL
Fiche technique Fiche technique

DUOX1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6966424
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1130711
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Pig
Analytical Method
Validations
N° du produit ABIN1130710
Quantité 96 tests
Fiche technique Fiche technique

DUOX1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1352080
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3079277
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3079276
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits DUOX1

Rivet, Kniss-James, Gran, Potnis, Hill, Lu, Kemp: "Calcium Dynamics of Ex Vivo Long-Term Cultured CD8+ T Cells Are Regulated by Changes in Redox Metabolism." dans: PLoS ONE, Vol. 11, Issue 8, pp. e0159248, (2016) (PubMed).

Wakatsuki, Furuno, Ohshima, Araki: "Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration." dans: The Journal of cell biology, Vol. 211, Issue 4, pp. 881-96, (2015) (PubMed).

Kippner, Finn, Shukla, Kemp: "Systemic remodeling of the redox regulatory network due to RNAi perturbations of glutaredoxin 1, thioredoxin 1, and glucose-6-phosphate dehydrogenase." dans: BMC systems biology, Vol. 5, pp. 164, (2011) (PubMed).

Harper, Xu, Eiserich, Chen, Kao, Thai, Setiadi, Wu: "Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium." dans: FEBS letters, Vol. 579, Issue 21, pp. 4911-7, (2005) (PubMed).

Synonymes et noms alternatifs relatifs à DUOX1

dual oxidase 1 (duox1), dual oxidase 1 (DUOX1), dual oxidase (duox), dual oxidase (LOC5569378), dual oxidase 1 (Duox1), 9930101G15Rik, AW987690, duox1, Duox2, LNOX1, LNOX2, NOXEF1, NOXEF2, P138-TOX, THOX1, THOX2, Udx1

Protein level used designations for DUOX1

  • dual oxidase 1
  • NADPH thyroid oxidase 1
  • flavoprotein NADPH oxidase
  • large NOX 1
  • long NOX 1
  • nicotinamide adenine dinucleotide phosphate oxidase
  • thyroid oxidase 1
  • dual oxidase 2
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