DUOX1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

N° du produit ABIN2719809

Détail du produit

Antigène: DUOX1 (Dual Oxidase 1 (DUOX1))

Type de proteíne: Recombinant

Attributs du protein: Transcript Variant 2

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette DUOX1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human Dual oxidase 1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: DUOX1 (Dual Oxidase 1 (DUOX1))

Autre désignation: Dual Oxidase 1 (DUOX1 Produits)

Synonymes: Udx1 Protein, duox1 Protein, LNOX1 Protein, NOXEF1 Protein, THOX1 Protein, 9930101G15Rik Protein, AW987690 Protein, Duox2 Protein, LNOX2 Protein, NOXEF2 Protein, P138-TOX Protein, THOX2 Protein, dual oxidase 1 Protein, dual oxidase Protein, duox1 Protein, DUOX1 Protein, duox Protein, LOC5569378 Protein, Duox1 Protein

Sujet: The protein encoded by this gene is a glycoprotein and a member of the NADPH oxidase family. The synthesis of thyroid hormone is catalyzed by a protein complex located at the apical membrane of thyroid follicular cells. This complex contains an iodide transporter, thyroperoxidase, and a peroxide generating system that includes proteins encoded by this gene and the similar DUOX2 gene. This protein is known as dual oxidase because it has both a peroxidase homology domain and a gp91phox domain. This protein generates hydrogen peroxide and thereby plays a role in the activity of thyroid peroxidase, lactoperoxidase, and in lactoperoxidase-mediated antimicrobial defense at mucosal surfaces. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

Poids moléculaire: 177.1 kDa

NCBI Accession: NP_787954