FANCD2 Produits
(Fanconi Anemia, Complementation Group D2 (FANCD2))
Catégories
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories FANCD2 en vedette
FANCD2 Anticorps
High quality antibodies with extensive validation data.
FANCD2 Kits ELISA
Reliable ELISA kits for a wide range of species.
FANCD2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IF, IHC (p), IP
Validations
- (5)
- (4)
N° du produit
ABIN540721
Quantité
50 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse
Application
WB, IHC, IF, IP, ICC
Validations
- (6)
N° du produit
ABIN363390
Quantité
0.05 mL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, IP
Validations
- (4)
N° du produit
ABIN3022849
Quantité
100 μL
Fiche technique
Fiche technique
FANCD2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380171
Quantité
2 x 96 tests
Fiche technique
Fiche technique
FANCD2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3092566
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3136034
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7424686
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits FANCD2
: "Multiplexed CRISPR/Cas9-mediated knockout of 19 Fanconi anemia pathway genes in zebrafish revealed their roles in growth, sexual development and fertility." dans: PLoS genetics, Vol. 14, Issue 12, pp. e1007821, (2019) (PubMed).: "Lnk/Sh2b3 deficiency restores hematopoietic stem cell function and genome integrity in Fancd2 deficient Fanconi anemia." dans: Nature communications, Vol. 9, Issue 1, pp. 3915, (2019) (PubMed).
: "Mammalian INO80 chromatin remodeler cooperates with FANCM to mediate DNA interstrand crosslink-induced checkpoint activation and repair." dans: DNA repair, Vol. 74, pp. 38-50, (2019) (PubMed).
: "Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability." dans: Nucleic acids research, (2019) (PubMed).
: "Chlorambucil targets BRCA1/2-deficient tumours and counteracts PARP inhibitor resistance. ..." dans: EMBO molecular medicine, (2019) (PubMed).
: "Remodeling of Interstrand Crosslink Proximal Replisomes Is Dependent on ATR, FANCM, and FANCD2." dans: Cell reports, Vol. 27, Issue 6, pp. 1794-1808.e5, (2019) (PubMed).
: "Dicer prevents genome instability in response to replication stress." dans: Oncotarget, Vol. 10, Issue 43, pp. 4407-4423, (2019) (PubMed).
: "FAN1 interaction with ubiquitylated PCNA alleviates replication stress and preserves genomic integrity independently of BRCA2." dans: Nature communications, Vol. 8, Issue 1, pp. 1073, (2018) (PubMed).
: "Fanconi anemia core complex-dependent HES1 mono-ubiquitination regulates its transcriptional activity." dans: BMC research notes, Vol. 11, Issue 1, pp. 138, (2018) (PubMed).
: "Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2." dans: Molecular cell, Vol. 71, Issue 1, pp. 25-41.e6, (2018) (PubMed).
Synonymes et noms alternatifs relatifs à FANCD2
Fanconi anemia complementation group D2 (FANCD2), CG17269 gene product from transcript CG17269-RA (Fancd2), Fanconi anemia group D2 protein (LOC100455970), Fanconi anemia complementation group D2 (fancd2), Fanconi anemia, complementation group D2 (fancd2), Fanconi anemia complementation group D2 L homeolog (fancd2.L), Fanconi anemia, complementation group D2 (FANCD2), Fanconi anemia, complementation group D2 (Fancd2), 2410150O07Rik, AU015151, BB137857, CG17269, CG31192, CG31194, Dmel\\CG17269, dmFANCD2, FA-D2, FA4, FACD, FAD, FAD2, FANCD, FANCD2, xfancd2Protein level used designations for FANCD2
- Fanconi anemia, complementation group D2
- CG17269-PA
- Fancd2-PA
- Fanconi anemia group D2 protein-like
- fanconi anemia protein FANCD2
- Fanconi anemia complementation group D2
- Fanconi anemia group D2 protein
- Fanconi anemia group D2 protein homolog
- Fanconi anemia D2 protein
Avez-vous cherché autre chose?
- FANCC
- FANCB
- FANCA
- FAN1
- Family with Sequence Similarity 92, Member A1
- Family with Sequence Similarity 69, Member C
- Family with Sequence Similarity 58, Member B
- Family with Sequence Similarity 50, Member A
- Family with Sequence Similarity 46, Member B
- Family with Sequence Similarity 220, Member A
- Family with Sequence Similarity 212, Member A
- Family with Sequence Similarity 21, Member B
- Family with Sequence Similarity 102, Member B
- Family with Sequence Similarity 102, Member A
- FAM9C
- FAM9B
- FAM9A
- FAM98C
- FAM98B
- FAM98A
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