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Fascin Produits

(Fascin (FSCN1))
This gene encodes a member of the fascin family of actin-binding proteins. Fascin proteins organize F-actin into parallel bundles, and are required for the formation of actin-based cellular protrusions. The encoded protein plays a critical role in cell migration, motility, adhesion and cellular interactions. Expression of this gene is known to be regulated by several microRNAs, and overexpression of this gene may play a role in the metastasis of multiple types of cancer by increasing cell motility. Expression of this gene is also a marker for Reed-Sternberg cells in Hodgkin's lymphoma. A pseudogene of this gene is located on the long arm of chromosome 15. [provided by RefSeq, Sep 2011].

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Catégories Fascin en vedette

Fascin Anticorps

High quality antibodies with extensive validation data.

Fascin Kits ELISA

Reliable ELISA kits for a wide range of species.

Fascin Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

Fascin recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, FACS, IF, StM
Validations
  • (7)
N° du produit ABIN6940607
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, IHC, FACS, IF, StM
Validations
  • (6)
N° du produit ABIN6940609
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (7)
N° du produit ABIN7267142
Quantité 100 μL
Fiche technique Fiche technique

Fascin recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6955706
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Dog
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN991658
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Goat
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN991657
Quantité 96 tests
Fiche technique Fiche technique

Fascin recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122887
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1989775
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3080239
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits Fascin

Zhang, Zhao, Zhang, Hao, Yu, Min, Li, Ma, Chen, Yi, Tang, Meng, Liu, Wang, Shen, Zhang: "Decrease in male mouse fertility by hydrogen sulfide and/or ammonia can Be inheritable." dans: Chemosphere, Vol. 194, pp. 147-157, (2018) (PubMed).

Yang, Teng, Han, Li, Yue, Wang: "Clinical significance of fascin-1 and laminin-5 in non-small cell lung cancer." dans: Genetics and molecular research : GMR, Vol. 16, Issue 2, (2017) (PubMed).

Barnawi, Al-Khaldi, Majed Sleiman, Sarkar, Al-Dhfyan, Al-Mohanna, Ghebeh, Al-Alwan: "Fascin Is Critical for the Maintenance of Breast Cancer Stem Cell Pool Predominantly via the Activation of the Notch Self-Renewal Pathway." dans: Stem cells (Dayton, Ohio), Vol. 34, Issue 12, pp. 2799-2813, (2016) (PubMed).

Osanai, Lee: "The retinoic acid-metabolizing enzyme CYP26A1 upregulates fascin and promotes the malignant behavior of breast carcinoma cells." dans: Oncology reports, Vol. 34, Issue 2, pp. 850-8, (2015) (PubMed).

Król, Mucha, Majchrzak, Homa, Bulkowska, Majewska, Gajewska, Pietrzak, Perszko, Romanowska, Paw?owski, Manuali, Hellmen, Motyl: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." dans: PLoS ONE, Vol. 9, Issue 1, pp. e83995, (2014) (PubMed).

Al-Masri, El Eter, Tayel, Zamil: "Differential associations of circulating peroxiredoxins levels with indicators of glycemic control in type 2 diabetes mellitus." dans: European review for medical and pharmacological sciences, Vol. 18, Issue 5, pp. 710-6, (2014) (PubMed).

Jiang, Wang, Chen: "Overexpression of FOXM1 is associated with metastases of nasopharyngeal carcinoma." dans: Upsala journal of medical sciences, Vol. 119, Issue 4, pp. 324-32, (2014) (PubMed).

Majchrzak, Lo Re, Gajewska, Bulkowska, Homa, Paw?owski, Motyl, Murphy, Król: "Migrastatin analogues inhibit canine mammary cancer cell migration and invasion." dans: PLoS ONE, Vol. 8, Issue 10, pp. e76789, (2013) (PubMed).

Teng, Xu, Yue, Ma, Zhang, Zhao, Guo, Zhang, Gu, Wang: "Serological investigation of the clinical significance of fascin in non-small-cell lung cancer." dans: Lung cancer (Amsterdam, Netherlands), Vol. 82, Issue 2, pp. 346-52, (2013) (PubMed).

Law, Li, Chou, Chen, Chan: "Hyaluronic acid-dependent protection in H9C2 cardiomyocytes: a cell model of heart ischemia-reperfusion injury and treatment." dans: Toxicology, Vol. 303, pp. 54-71, (2013) (PubMed).

Synonymes et noms alternatifs relatifs à Fascin

singed (sn), fascin actin-bundling protein 1 (fscn1), fascin actin-bundling protein 1a (fscn1a), fascin actin-bundling protein 1 (Fscn1), fascin actin-bundling protein 1 L homeolog (fscn1.L), fascin actin-bundling protein 1 (FSCN1), AI663989, CG1536, CG15331, CG32858, Dmel\\CG32858, Fan1, FAN1, Fascin, fascin, fascin-1, fs(1)A1057, fs(1)K418, fs(1)K473, fs(1)K743, fs(1)K1421, fs(1)M45, fscn, fscn1, HSN, MGC75811, p55, sb:cb589, SN, Sn, snl, SNL, zgc:153632

Protein level used designations for Fascin

  • CG32858-PA
  • CG32858-PB
  • CG32858-PD
  • CG32858-PE
  • CG32858-PF
  • CG32858-PG
  • fascin
  • sn-PA
  • sn-PB
  • sn-PD
  • sn-PE
  • sn-PF
  • sn-PG
  • fascin-1
  • fascin 1
  • singed-like protein
  • 55 kDa actin-bundling protein
  • singed-like (fascin homolog, sea urchin)
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