FAP Produits
(Fibroblast Activation Protein, alpha (FAP))
Catégories
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. [provided by RefSeq, Jul 2008].
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Catégories FAP en vedette
FAP Anticorps
High quality antibodies with extensive validation data.
FAP Kits ELISA
Reliable ELISA kits for a wide range of species.
FAP Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FAP recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, FACS
Validations
- (6)
N° du produit
ABIN7193479
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (4)
- (5)
N° du produit
ABIN560844
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7434938
Quantité
100 μL
Fiche technique
Fiche technique
FAP recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955802
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955800
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955801
Quantité
96 tests
Fiche technique
Fiche technique
FAP recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7274584
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
N° du produit
ABIN7274585
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (3)
N° du produit
ABIN7274586
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits FAP
: "Exploring Metabolic Configurations of Single Cells within Complex Tissue Microenvironments." dans: Cell metabolism, Vol. 26, Issue 5, pp. 788-800.e6, (2017) (PubMed).: "TNF-α promotes breast cancer cell migration and enhances the concentration of membrane-associated proteases in lipid rafts." dans: Cellular oncology (Dordrecht), Vol. 39, Issue 4, pp. 353-63, (2017) (PubMed).
: "Enhanced Antitumor Activity of EGFP-EGF1-Conjugated Nanoparticles by a Multitargeting Strategy." dans: ACS applied materials & interfaces, Vol. 8, Issue 14, pp. 8918-27, (2016) (PubMed).
: "Endothelial to mesenchymal transition is common in atherosclerotic lesions and is associated with plaque instability." dans: Nature communications, Vol. 7, pp. 11853, (2016) (PubMed).
: "Growth differentiation factor 15 contributes to cancer-associated fibroblasts-mediated chemo-protection of AML cells." dans: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 147, (2016) (PubMed).
: "FAP Promotes Immunosuppression by Cancer-Associated Fibroblasts in the Tumor Microenvironment via STAT3-CCL2 Signaling." dans: Cancer research, Vol. 76, Issue 14, pp. 4124-35, (2016) (PubMed).
: "Extracellular Hsp90 mediates an NF-?B dependent inflammatory stromal program: implications for the prostate tumor microenvironment." dans: The Prostate, Vol. 74, Issue 4, pp. 395-407, (2014) (PubMed).
: "Fibroblast activation protein (FAP) is essential for the migration of bone marrow mesenchymal stem cells through RhoA activation." dans: PLoS ONE, Vol. 9, Issue 2, pp. e88772, (2014) (PubMed).
: "Protumorigenic effects of Snail-expression fibroblasts on colon cancer cells." dans: International journal of cancer, Vol. 134, Issue 12, pp. 2984-90, (2014) (PubMed).
: "Cancer-associated fibroblast and M2 macrophage markers together predict outcome in colorectal cancer patients." dans: Cancer science, Vol. 104, Issue 4, pp. 437-44, (2013) (PubMed).
Synonymes et noms alternatifs relatifs à FAP
fibroblast activation protein (Fap), fibroblast activation protein alpha L homeolog (fap.L), fibroblast activation protein alpha (FAP), fibroblast activation protein, alpha (Fap), fibroblast activation protein alpha (fap), prolyl endopeptidase FAP (LOC100547273), fibroblast activation protein alpha (Fap), dppiv, DPPIV, FAP, fap-A, fapa, FAPA, gene 13, sepraseProtein level used designations for FAP
- fibroblast activation protein alpha
- integral membrane serine protease
- seprase
- fibroblast activation protein, alpha
- fibroblast activation protein, alpha subunit
- gene 13
- 170 kDa melanoma membrane-bound gelatinase
- seprase-like
- prolyl endopeptidase FAP
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- FAN1
- Family with Sequence Similarity 92, Member A1
- Family with Sequence Similarity 69, Member C
- Family with Sequence Similarity 58, Member B
- Family with Sequence Similarity 50, Member A
- Family with Sequence Similarity 46, Member B
- Family with Sequence Similarity 220, Member A
- Family with Sequence Similarity 212, Member A
- Family with Sequence Similarity 21, Member B
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