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FLI1 Produits

(Friend Leukemia Virus Integration 1 (FLI1))
This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11\;22)(q24\;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4\;11)(q21\;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012].

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Catégories FLI1 en vedette

FLI1 Anticorps

High quality antibodies with extensive validation data.

FLI1 Kits ELISA

Reliable ELISA kits for a wide range of species.

FLI1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FLI1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IHC, FACS
Validations
  • (6)
N° du produit ABIN7193672
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application WB
Validations
  • (1)
  • (4)
N° du produit ABIN2780392
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Rat
Application WB, IHC (p)
Validations
  • (1)
  • (4)
N° du produit ABIN3043998
Quantité 100 μg
Fiche technique Fiche technique

FLI1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1114985
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1381141
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative DNA-Binding ELISA
Validations
N° du produit ABIN5648544
Quantité 96 tests
Fiche technique Fiche technique

FLI1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123005
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3133466
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3080222
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits FLI1

Choi, El-Hamdi, McGregor: "Endothelial Cell Infection by Guinea Pig Cytomegalovirus Is a Lytic or Persistent Infection Depending on Tissue Origin but Requires Viral Pentamer Complex and pp65 Tegument Protein." dans: Journal of virology, Vol. 96, Issue 17, pp. e0083122, (2022) (PubMed).

Radic-Sarikas, Tsafou, Emdal, Papamarkou, Huber, Mutz, Toretsky, Bennett, Olsen, Brunak, Kovar, Superti-Furga: "Combinatorial Drug Screening Identifies Ewing Sarcoma-specific Sensitivities." dans: Molecular cancer therapeutics, Vol. 16, Issue 1, pp. 88-101, (2017) (PubMed).

Bujor, Haines, Padilla, Christmann, Junie, Sampaio-Barros, Lafyatis, Trojanowska: "Ciprofloxacin has antifibrotic effects in scleroderma fibroblasts via downregulation of Dnmt1 and upregulation of Fli1." dans: International journal of molecular medicine, Vol. 30, Issue 6, pp. 1473-80, (2012) (PubMed).

McKinsey, Parrish, Irwin, Niemeyer, Kern, Birks, Jedlicka: "A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs." dans: Oncogene, Vol. 30, Issue 49, pp. 4910-20, (2011) (PubMed).

Bailly, Bosselut, Zucman, Cormier, Delattre, Roussel, Thomas, Ghysdael: "DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma." dans: Molecular and cellular biology, Vol. 14, Issue 5, pp. 3230-41, (1994) (PubMed).

May, Lessnick, Braun, Klemsz, Lewis, Lunsford, Hromas, Denny: "The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1." dans: Molecular and cellular biology, Vol. 13, Issue 12, pp. 7393-8, (1994) (PubMed).

Synonymes et noms alternatifs relatifs à FLI1

Fli-1 proto-oncogene, ETS transcription factor (FLI1), Fli-1 proto-oncogene, ETS transcription factor (Fli1), Fli-1 proto-oncogene, ETS transcription factor S homeolog (fli1.S), Fli-1 proto-oncogene, ETS transcription factor (fli1), Friend leukemia integration 1 (Fli1), Fli-1 proto-oncogene, ETS transcription factor a (fli1a), Fli-1 proto-oncogene, ETS transcription factor L homeolog (fli1.L), cb855, EWSR2, fli, fli-1, Fli-1, FLI1, fli1, MGC121593, SIC-1, Sic1, wu:fc45b11, Xfli, Xfli-1, Xfli1, xlfli

Protein level used designations for FLI1

  • Ewing sarcoma breakpoint region 2
  • Friend leukemia integration 1 transcription factor
  • Friend leukemia virus integration 1
  • proto-oncogene Fli-1
  • transcription factor ERGB
  • fli-1 proto-oncogene
  • friend leukemia integration 1 transcription factor-like
  • Friend leukemia integration 1 transcription factor-like
  • retroviral integration site protein Fli-1
  • retroviral integration site protein Fli-1 homolog
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