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FKBP5 Produits

(FK506 Binding Protein 5 (FKBP5))

Catégories

The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009].

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Catégories FKBP5 en vedette

FKBP5 Anticorps

High quality antibodies with extensive validation data.

FKBP5 Kits ELISA

Reliable ELISA kits for a wide range of species.

FKBP5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

FKBP5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IF, IHC (p)
Validations
  • (3)
  • (6)
N° du produit ABIN515669
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (6)
N° du produit ABIN7260887
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB
Validations
  • (7)
N° du produit ABIN1679852
Quantité 100 μg
Fiche technique Fiche technique

FKBP5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955923
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6955924
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN4882891
Quantité 96 tests
Fiche technique Fiche technique

FKBP5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
N° du produit ABIN1354130
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7122977
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3080248
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits FKBP5

Mata-Greenwood, Jackson, Pearce, Zhang: "Endothelial glucocorticoid receptor promoter methylation according to dexamethasone sensitivity." dans: Journal of molecular endocrinology, (2015) (PubMed).

Romano, Xiao, Nakaya, DAngelillo, Chang, Jin, Hausch, Masullo, Feng, Romano, Sun: "FKBP51 employs both scaffold and isomerase functions to promote NF-?B activation in melanoma." dans: Nucleic acids research, Vol. 43, Issue 14, pp. 6983-93, (2015) (PubMed).

Romano, DAngelillo, Staibano, Simeone, DArrigo, Ascierto, Scalvenzi, Mascolo, Ilardi, Merolla, Jovarauskaite, Romano: "Immunomodulatory pathways regulate expression of a spliced FKBP51 isoform in lymphocytes of melanoma patients." dans: Pigment cell & melanoma research, Vol. 28, Issue 4, pp. 442-52, (2015) (PubMed).

Yang, Zhang, Pei, Xu, Li, Yu: "FK506-binding protein 5 inhibits proliferation and stimulates apoptosis of glioma cells." dans: Archives of medical science : AMS, Vol. 11, Issue 5, pp. 1074-80, (2015) (PubMed).

Romano, DAngelillo, DArrigo, Staibano, Greco, Brunetti, Scalvenzi, Bisogni, Scala, Romano: "FKBP51 increases the tumour-promoter potential of TGF-beta." dans: Clinical and translational medicine, Vol. 3, Issue 1, pp. 1, (2014) (PubMed).

Romano, Staibano, Greco, Brunetti, Nappo, Ilardi, Martinelli, Sorrentino, Di Pace, Mascolo, Bisogni, Scalvenzi, Alfano, Romano: "FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential." dans: Cell death & disease, Vol. 4, pp. e578, (2013) (PubMed).

van Lierop, Alkema, Laskewitz, Dijkema, van der Maaden, Smit, Plate, Conti, Jans, Timmers, van Boeckel, Lusher, McGuire, van Schaik, de Vlieg, Smeets, Hofstra, Boots, van Duin, Ingelse, Schoonen et al.: "Org 214007-0: a novel non-steroidal selective glucocorticoid receptor modulator with full anti-inflammatory properties and improved therapeutic index. ..." dans: PLoS ONE, Vol. 7, Issue 11, pp. e48385, (2012) (PubMed).

Horibe, Kohno, Haramoto, Ohara, Kawakami: "Designed hybrid TPR peptide targeting Hsp90 as a novel anticancer agent." dans: Journal of translational medicine, Vol. 9, pp. 8, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à FKBP5

FK506 binding protein 5 (FKBP5), FK506 binding protein 5 (fkbp5), FK506 binding protein 5 (Fkbp5), AIG6, D17Ertd592e, Dit1, FKBP-5, FKBP5, FKBP51, FKBP54, P54, PPIase, Ptg-10, si:zc263a23.8, wu:fc31g11, wu:fl87b03, zgc:64082

Protein level used designations for FKBP5

  • FK506 binding protein 5
  • FK506-binding protein 5
  • PPIase FKBP5
  • peptidyl-prolyl cis-trans isomerase FKBP5
  • rotamase
  • 51 kDa FK506-binding protein 5
  • 51 kDa FKBP
  • 54 kDa progesterone receptor-associated immunophilin
  • FF1 antigen
  • FKBP-5
  • FKBP-51
  • HSP90-binding immunophilin
  • T-cell FK506-binding protein
  • androgen-regulated protein 6
  • peptidylprolyl cis-trans isomerase
  • 51 kDa FK506-binding protein
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