FZD1 Produits
(Frizzled Family Receptor 1 (Fzd1))
Catégories
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK- 3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. Activated by Wnt3A, Wnt3, Wnt1 and to a lesser extent Wnt2, but not by Wnt4, Wnt5A, Wnt5B, Wnt6, Wnt7A or Wnt7B.
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Catégories FZD1 en vedette
FZD1 Anticorps
High quality antibodies with extensive validation data.
FZD1 Kits ELISA
Reliable ELISA kits for a wide range of species.
FZD1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
FZD1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (8)
N° du produit
ABIN7435805
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (4)
N° du produit
ABIN7153179
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
N° du produit
ABIN7153175
Quantité
100 μg
Fiche technique
Fiche technique
FZD1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6966904
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6955998
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
N° du produit
ABIN6730674
Quantité
96 tests
Fiche technique
Fiche technique
FZD1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
N° du produit
ABIN7320532
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
N° du produit
ABIN7195855
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Insect Cells
Validations
- (1)
N° du produit
ABIN3080339
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits FZD1
: "Overexpression of FZD1 and CAIX are Associated with Invasion, Metastasis, and Poor-Prognosis of the Pancreatic Ductal Adenocarcinoma." dans: Pathology oncology research : POR, Vol. 24, Issue 4, pp. 899-906, (2018) (PubMed).: "Transcriptional Regulation of Frizzled-1 in Human Osteoblasts by Sp1." dans: PLoS ONE, Vol. 11, Issue 10, pp. e0163277, (2017) (PubMed).
: "β-Catenin-dependent pathway activation by both promiscuous "canonical" WNT3a-, and specific "noncanonical" WNT4- and WNT5a-FZD receptor combinations with strong differences in LRP5 and LRP6 ..." dans: Cellular signalling, Vol. 26, Issue 2, pp. 260-7, (2013) (PubMed).
: "Functional and association analysis of frizzled 1 (FZD1) promoter haplotypes with femoral neck geometry." dans: Bone, Vol. 46, Issue 4, pp. 1131-7, (2010) (PubMed).
: "Secreted Frizzled-related protein-1 is a negative regulator of androgen receptor activity in prostate cancer." dans: British journal of cancer, Vol. 100, Issue 7, pp. 1165-74, (2009) (PubMed).
: "A cryptic frizzled module in cell surface collagen 18 inhibits Wnt/beta-catenin signaling." dans: PLoS ONE, Vol. 3, Issue 4, pp. e1878, (2008) (PubMed).
: "Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis." dans: American journal of respiratory cell and molecular biology, Vol. 37, Issue 3, pp. 309-21, (2007) (PubMed).
: "R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 37, pp. 14700-5, (2007) (PubMed).
: "Cross-talk between Wnt signaling pathways in human mesenchymal stem cells leads to functional antagonism during osteogenic differentiation." dans: Journal of cellular biochemistry, Vol. 101, Issue 5, pp. 1109-24, (2007) (PubMed).
: "Bone morphogenetic protein-2 modulates Wnt and frizzled expression and enhances the canonical pathway of Wnt signaling in normal keratinocytes." dans: Journal of dermatological science, Vol. 42, Issue 2, pp. 111-9, (2006) (PubMed).
Synonymes et noms alternatifs relatifs à FZD1
frizzled (fz), frizzled class receptor 1 (FZD1), frizzled class receptor 1 (Fzd1), frizzled class receptor 1 L homeolog (fzd1.L), AW227548, cFz-1, CG3646, CG17697, DFz, DFZ1, DFz1, Dfz1, Dmel\\CG17697, Dm Fz1, frizzled1, Frz, frz, frz-1, frz1, FZ, Fz, Fz-1, FZ-1, Fz1, fz1, fzd1-A, fz[[1]], Xfrizzled-1Protein level used designations for FZD1
- CG17697-PA
- CG17697-PB
- CG17697-PC
- Frizzled1
- frazzled
- frizzled 1
- frizzled[[1]]
- fz-PA
- fz-PB
- fz-PC
- frizzled 1, seven transmembrane spanning receptor
- frizzled homolog 1
- Wnt receptor
- frizzled, Drosophila, homolog of, 1
- frizzled-1
- fz-1
- fzE1
- hFz1
- 7-transmembrane protein frizzled-1
- Drosophila polarity gene (frizzled) homologue
- Drosophila polarity gene homolog 1
- rFz1
- 7-transmembrane receptor frizzled-1
- xfz1
- mFz1
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