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GABBR1 Produits

(gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Catégories

Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. [provided by RefSeq, Jun 2009].

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Catégories GABBR1 en vedette

GABBR1 Anticorps

High quality antibodies with extensive validation data.

GABBR1 Kits ELISA

Reliable ELISA kits for a wide range of species.

GABBR1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GABBR1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF, RNAi
Validations
  • (4)
  • (6)
N° du produit ABIN560976
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IF, ICC, IHC (p)
Validations
  • (4)
N° du produit ABIN2855413
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF, IHC, ICC
Validations
  • (4)
N° du produit ABIN6261856
Quantité 100 μL
Fiche technique Fiche technique

GABBR1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6956037
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1134286
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1134287
Quantité 96 tests
Fiche technique Fiche technique

GABBR1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1354631
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1354630
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3092656
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits GABBR1

Ullrich, Göhmann, Zemella, Kubick: "Oligomerization of the heteromeric γ-aminobutyric acid receptor GABAB in a eukaryotic cell-free system." dans: Scientific reports, Vol. 12, Issue 1, pp. 20742, (2022) (PubMed).

Zhou, Chen, Liu, Manyande, Zhang, Yang, Xiong, Fu, Song, Rittner, Ye, Tian: "The Role of Spinal GABAB Receptors in Cancer-Induced Bone Pain in Rats." dans: The journal of pain : official journal of the American Pain Society, Vol. 18, Issue 8, pp. 933-946, (2018) (PubMed).

Karls, Mynlieff: "GABAB receptors couple to Gαq to mediate increases in voltage-dependent calcium current during development." dans: Journal of neurochemistry, (2015) (PubMed).

Huynh, Cuny, Slesinger, Adams: "Novel mechanism of voltage-gated N-type (Cav2.2) calcium channel inhibition revealed through α-conotoxin Vc1.1 activation of the GABA(B) receptor." dans: Molecular pharmacology, Vol. 87, Issue 2, pp. 240-50, (2015) (PubMed).

Yu, Seymour, Berecki, Jia, Akcan, Adams, Kaas, Craik: "Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1." dans: Scientific reports, Vol. 5, pp. 13264, (2015) (PubMed).

Ariño, Höftberger, Gresa-Arribas, Martínez-Hernández, Armangue, Kruer, Arpa, Domingo, Rojc, Bataller, Saiz, Dalmau, Graus: "Paraneoplastic Neurological Syndromes and Glutamic Acid Decarboxylase Antibodies." dans: JAMA neurology, Vol. 72, Issue 8, pp. 874-81, (2015) (PubMed).

Dogan Onugoren, Deuretzbacher, Haensch, Hagedorn, Halve, Isenmann, Kramme, Lohner, Melzer, Monotti, Presslauer, Schäbitz, Steffanoni, Stoeck, Strittmatter, Stögbauer, Trinka, von Oertzen, Wiendl et al.: "Limbic encephalitis due to GABAB and AMPA receptor antibodies: a case series. ..." dans: Journal of neurology, neurosurgery, and psychiatry, (2014) (PubMed).

Dogan Onugoren, Rauschka, Bien: "Conjoint occurrence of GABAB receptor antibodies in Lambert-Eaton myasthenic syndrome with antibodies to the voltage gated calcium channel." dans: Journal of neuroimmunology, Vol. 273, Issue 1-2, pp. 115-6, (2014) (PubMed).

Terunuma, Revilla-Sanchez, Quadros, Deng, Deeb, Lumb, Sicinski, Haydon, Pangalos, Moss: "Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 3, pp. 804-16, (2014) (PubMed).

Wang, Chen, Chen, Wolpaw, Chen: "Cortical stimulation causes long-term changes in H-reflexes and spinal motoneuron GABA receptors." dans: Journal of neurophysiology, Vol. 108, Issue 10, pp. 2668-78, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à GABBR1

gamma-aminobutyric acid type B receptor subunit 1 (GABBR1), gamma-aminobutyric acid (GABA) B receptor, 1a (gabbr1a), gamma-aminobutyric acid (GABA) B receptor, 1 (gabbr1), gamma-aminobutyric acid type B receptor subunit 1 (Gabbr1), gamma-aminobutyric acid (GABA) B receptor, 1 (GABBR1), gamma-aminobutyric acid (GABA) B receptor, 1 (Gabbr1), bM573K1.1, dJ271M21.1.1, dJ271M21.1.2, GABA(B)R1, GABAB1, GABABR1, GABAbR1, gabbr1, GABBR1, GABBR1-3, GB1, GPRC3A

Protein level used designations for GABBR1

  • GABA-BR1
  • GABAB, subunit 1c
  • gamma-aminobutyric acid type B receptor subunit 1
  • seven transmembrane helix receptor
  • gamma-aminobutyric acid (GABA) B receptor, 1
  • gaba1
  • gamma-aminobutyric acid (GABA) B receptor 1
  • gamma-aminobutyric acid B receptor 1
  • GABA-B receptor 1
  • GABA-B-R1
  • GABABR1
  • gb1
  • GABA-BR1b receptor
  • bM573K1.1.1 (gamma-aminobutyric acid (GABA) B receptor, 1a)
  • gamma-aminobutyric acid (GABA-B) receptor, 1
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