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GABBR2 Produits

(gamma-aminobutyric Acid (GABA) B Receptor, 2 (GABBR2))
The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010].

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Catégories GABBR2 en vedette

GABBR2 Anticorps

High quality antibodies with extensive validation data.

GABBR2 Kits ELISA

Reliable ELISA kits for a wide range of species.

GABBR2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GABBR2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, ELISA, ICC
Validations
  • (1)
  • (5)
N° du produit ABIN1724937
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (3)
N° du produit ABIN674544
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
N° du produit ABIN654172
Quantité 400 μL
Fiche technique Fiche technique

GABBR2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method
Validations
N° du produit ABIN1134289
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Mouse
Analytical Method
Validations
N° du produit ABIN1134290
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method
Validations
N° du produit ABIN1134291
Quantité 96 tests
Fiche technique Fiche technique

GABBR2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1354633
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3092701
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN3135974
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits GABBR2

Zhou, Chen, Liu, Manyande, Zhang, Yang, Xiong, Fu, Song, Rittner, Ye, Tian: "The Role of Spinal GABAB Receptors in Cancer-Induced Bone Pain in Rats." dans: The journal of pain : official journal of the American Pain Society, Vol. 18, Issue 8, pp. 933-946, (2018) (PubMed).

Marron Fernandez de Velasco, Hearing, Xia, Victoria, Luján, Wickman: "Sex differences in GABABR-GIRK signaling in layer 5/6 pyramidal neurons of the mouse prelimbic cortex." dans: Neuropharmacology, Vol. 95, pp. 353-60, (2015) (PubMed).

Workman, Haddick, Bush, Dilly, Niere, Zemelman, Raab-Graham: "Rapid antidepressants stimulate the decoupling of GABA(B) receptors from GIRK/Kir3 channels through increased protein stability of 14-3-3η." dans: Molecular psychiatry, Vol. 20, Issue 3, pp. 298-310, (2015) (PubMed).

Huynh, Cuny, Slesinger, Adams: "Novel mechanism of voltage-gated N-type (Cav2.2) calcium channel inhibition revealed through α-conotoxin Vc1.1 activation of the GABA(B) receptor." dans: Molecular pharmacology, Vol. 87, Issue 2, pp. 240-50, (2015) (PubMed).

Yu, Seymour, Berecki, Jia, Akcan, Adams, Kaas, Craik: "Less is More: Design of a Highly Stable Disulfide-Deleted Mutant of Analgesic Cyclic α-Conotoxin Vc1.1." dans: Scientific reports, Vol. 5, pp. 13264, (2015) (PubMed).

Ariño, Höftberger, Gresa-Arribas, Martínez-Hernández, Armangue, Kruer, Arpa, Domingo, Rojc, Bataller, Saiz, Dalmau, Graus: "Paraneoplastic Neurological Syndromes and Glutamic Acid Decarboxylase Antibodies." dans: JAMA neurology, Vol. 72, Issue 8, pp. 874-81, (2015) (PubMed).

Terunuma, Revilla-Sanchez, Quadros, Deng, Deeb, Lumb, Sicinski, Haydon, Pangalos, Moss: "Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 34, Issue 3, pp. 804-16, (2014) (PubMed).

Murthy, Kim, Sun, Giger, Fink, Mata: "Post-transcriptional regulation of GABAB receptor and GIRK1 channels by Nogo receptor 1." dans: Molecular brain, Vol. 6, pp. 30, (2013) (PubMed).

Hearing, Kotecki, Marron Fernandez de Velasco, Fajardo-Serrano, Chung, Luján, Wickman: "Repeated cocaine weakens GABA(B)-Girk signaling in layer 5/6 pyramidal neurons in the prelimbic cortex." dans: Neuron, Vol. 80, Issue 1, pp. 159-70, (2013) (PubMed).

Paris-Robidas, Brochu, Sintes, Emond, Bousquet, Vandal, Pilote, Tremblay, Di Paolo, Rajput, Rajput, Calon: "Defective dentate nucleus GABA receptors in essential tremor." dans: Brain : a journal of neurology, Vol. 135, Issue Pt 1, pp. 105-16, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à GABBR2

gamma-aminobutyric acid type B receptor subunit 2 (GABBR2), gamma-aminobutyric acid (GABA) B receptor, 2 (GABBR2), gamma-aminobutyric acid type B receptor subunit 2 (LOC100448699), gamma-aminobutyric acid type B receptor subunit 2 (gabbr2), gamma-aminobutyric acid type B receptor subunit 2 (Gabbr2), gamma-aminobutyric acid (GABA) B receptor, 2 (Gabbr2), gamma-aminobutyric acid (GABA) B receptor, 2 S homeolog (gabbr2.S), gamma-aminobutyric acid (GABA) B receptor, 2 (gabbr2), GABA(B)R2, GABABR2, Gb2, Gm425, Gpr51, GPR51, GPRC3B, HG20, HRIHFB2099, si:dkey-190l1.2

Protein level used designations for GABBR2

  • gamma-aminobutyric acid (GABA) B receptor, 2
  • gamma-aminobutyric acid type B receptor subunit 2-like
  • G protein-coupled receptor 51
  • G-protein coupled receptor 51
  • GABA-B R2 receptor
  • GABA-B receptor 2
  • GABA-B-R2
  • GABA-BR2
  • GABABR2
  • gamma-aminobutyric acid type B receptor subunit 2
  • gb2
  • GABA-B receptor, R2 subunit
  • gamma-aminobutyric acid B receptor 2
  • gamma-aminobutyric acid type B receptor, subunit 2
  • ortholog of human G protein-coupled receptor 51 GPR51
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