GDNF Protéines
(Glial Cell Line Derived Neurotrophic Factor (GDNF))
This gene encodes a highly conserved neurotrophic factor. The recombinant form of this protein was shown to promote the survival and differentiation of dopaminergic neurons in culture, and was able to prevent apoptosis of motor neurons induced by axotomy. The encoded protein is processed to a mature secreted form that exists as a homodimer. The mature form of the protein is a ligand for the product of the RET (rearranged during transfection) protooncogene. Multiple transcript variants encoding different isoforms have been found for this gene. Mutations in this gene may be associated with Hirschsprung disease. [provided by RefSeq, Jun 2010].
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GDNF
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
WB, CC, FACS, FM, IF, LCI
Active
GDNF
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
AM, ADA, IA, ScA
1 image
GDNF
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
GDNF
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
Greater than 90 % as determined by SDS-PAGE.
WB, ELISA
1 image
GDNF
Origine: Humain
Hôte: Wheat germ
Recombinant
AP, AA, ELISA, WB
1 image
GDNF
Origine: Rat
Hôte: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
GDNF
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
GDNF
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
GDNF
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
GDNF
Origine: Macaque rhésus
Hôte: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
GDNF
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
GDNF
Origine: Souris
Hôte: CHO Cells
Recombinant
> 95 % as analyzed by SDS-PAGE and HPLC.
Active
GDNF
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 %
SDS, AcA
Active
GDNF
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
GDNF
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
>95 %
WB
Active
GDNF
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 90 % as determined by reducing SDS-PAGE.
Imm
GDNF
Origine: Humain
Hôte: Mammalian Cells
Recombinant
> 90 % as determined by reducing SDS-PAGE.
Imm
GDNF
Origine: Souris
Hôte: Escherichia coli (E. coli)
Recombinant
> 98 % as determined by reducing SDS-PAGE.
GDNF
Origine: Humain
Hôte: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
CC
Active
Dernières publications pour nos GDNF Protéines
: "A bioenergetic shift is required for spermatogonial differentiation." dans: Cell discovery, Vol. 6, pp. 56, (2020) (PubMed).
: "The morphological and molecular changes of brain cells exposed to direct current electric field stimulation." dans: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 18, Issue 5, (2015) (PubMed).
: "Multiple astrocyte transcripts encode nigral trophic factors in rat and human." dans: Experimental neurology, Vol. 130, Issue 2, pp. 387-93, (1995) (PubMed).
: "GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons." dans: Science (New York, N.Y.), Vol. 260, Issue 5111, pp. 1130-2, (1993) (PubMed).
: "The morphological and molecular changes of brain cells exposed to direct current electric field stimulation." dans: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 18, Issue 5, (2015) (PubMed).
: "Multiple astrocyte transcripts encode nigral trophic factors in rat and human." dans: Experimental neurology, Vol. 130, Issue 2, pp. 387-93, (1995) (PubMed).
: "GDNF: a glial cell line-derived neurotrophic factor for midbrain dopaminergic neurons." dans: Science (New York, N.Y.), Vol. 260, Issue 5111, pp. 1130-2, (1993) (PubMed).
Pseudonymes pour GDNF Protéines
glial cell derived neurotrophic factor (Gdnf) Protéinesglial cell derived neurotrophic factor a (gdnfa) Protéines
glial cell derived neurotrophic factor (GDNF) Protéines
glial cell line derived neurotrophic factor (Gdnf) Protéines
glial cell derived neurotrophic factor L homeolog (gdnf.L) Protéines
AI385739 Protéines
ATF1 Protéines
ATF2 Protéines
gdnf Protéines
GDNF Protéines
gdnfa Protéines
hfb1-gdnf Protéines
HFB1-GDNF Protéines
HSCR3 Protéines
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