GRB2 Produits
(Growth Factor Receptor-Bound Protein 2 (GRB2))
Catégories
The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Catégories GRB2 en vedette
GRB2 Anticorps
High quality antibodies with extensive validation data.
GRB2 Kits ELISA
Reliable ELISA kits for a wide range of species.
GRB2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GRB2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Chicken, Dog, Human, Mouse, Rat
Application
ELISA, IHC (p)
Validations
- (2)
- (1)
N° du produit
ABIN686932
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), IF, ICC
Validations
- (9)
N° du produit
ABIN2854697
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, IF
Validations
- (6)
N° du produit
ABIN7267518
Quantité
100 μL
Fiche technique
Fiche technique
GRB2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6956336
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967248
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380816
Quantité
2 x 96 tests
Fiche technique
Fiche technique
GRB2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1355702
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1355704
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3122684
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits GRB2
: "Regulation of insulin receptor phosphorylation in the brains of prenatally stressed rats: New insight into the benefits of antidepressant drug treatment." dans: European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, Vol. 27, Issue 2, pp. 120-131, (2017) (PubMed).: "Targeting the C-terminal focal adhesion kinase scaffold in pancreatic cancer." dans: Cancer letters, Vol. 353, Issue 2, pp. 281-9, (2014) (PubMed).
: "Recruitment of the adaptor protein Grb2 to EGFR tetramers." dans: Biochemistry, Vol. 53, Issue 16, pp. 2594-604, (2014) (PubMed).
: "An analysis of the phosphoproteome of immune cell lines exposed to the immunomodulatory mycotoxin deoxynivalenol." dans: Biochimica et biophysica acta, Vol. 1814, Issue 7, pp. 850-7, (2011) (PubMed).
: "The molecular basis of phospholipase D2-induced chemotaxis: elucidation of differential pathways in macrophages and fibroblasts." dans: Molecular and cellular biology, Vol. 30, Issue 18, pp. 4492-506, (2010) (PubMed).
: "Src-dependent TrkA transactivation is required for pituitary adenylate cyclase-activating polypeptide 38-mediated Rit activation and neuronal differentiation." dans: Molecular biology of the cell, Vol. 21, Issue 9, pp. 1597-608, (2010) (PubMed).
: "Coupling of Grb2 to Gab1 mediates hepatocyte growth factor-induced high intensity ERK signal required for inhibition of HepG2 hepatoma cell proliferation." dans: The Journal of biological chemistry, Vol. 283, Issue 3, pp. 1428-36, (2008) (PubMed).
: "Sprouty2 binds Grb2 at two different proline-rich regions, and the mechanism of ERK inhibition is independent of this interaction." dans: Cellular signalling, Vol. 19, Issue 11, pp. 2277-85, (2007) (PubMed).
: "Multiple-state reactions between the epidermal growth factor receptor and Grb2 as observed by using single-molecule analysis." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 46, pp. 18013-8, (2007) (PubMed).
: "Angiotensin II type 2 receptor-dependent increases in nitric oxide synthase expression in the pulmonary endothelium is mediated via a G alpha i3/Ras/Raf/MAPK pathway." dans: American journal of physiology. Cell physiology, Vol. 292, Issue 6, pp. C2185-96, (2007) (PubMed).
Synonymes et noms alternatifs relatifs à GRB2
growth factor receptor bound protein 2 (GRB2), growth factor receptor-bound protein 2 (grb2), growth factor receptor bound protein 2 (Grb2), growth factor receptor-bound protein 2b (grb2b), AA408164, Ash, ASH, EGFRBP-GRB2, GRB2, grb2, Grb3-3, MST084, MSTP084, NCKAP2, wu:fb18e12, wu:fb34e06, zgc:73077Protein level used designations for GRB2
- growth factor receptor-bound protein 2
- Growth factor receptor-bound protein 2
- SH2/SH3 adapter GRB2
- adapter protein GRB2
- protein Ash
- HT027
- abundant SRC homology
- epidermal growth factor receptor-binding protein GRB2
- growth factor receptor-bound protein 3
- growth factor receptor bound protein 2
- fb18e12
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