GRID2 Produits
(Glutamate Receptor, Ionotropic, delta 2 (GRID2))
Catégories
Human glutamate receptor delta-2 (GRID2) is a relatively new member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. GRID2 is a predicted 1,007 amino acid protein that shares 97% identity with the mouse homolog which is expressed selectively in cerebellar Purkinje cells. A point mutation in mouse GRID2, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This strongly suggests a role for GRID2 in neuronal apoptotic death. [provided by RefSeq, Jul 2008].
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Catégories GRID2 en vedette
GRID2 Anticorps
High quality antibodies with extensive validation data.
GRID2 Kits ELISA
Reliable ELISA kits for a wide range of species.
GRID2 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GRID2 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IF, ELISA, ICC, IHC
Validations
- (3)
N° du produit
ABIN6257247
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
N° du produit
ABIN561131
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IF, ELISA
Validations
- (1)
N° du produit
ABIN7184958
Quantité
100 μg
Fiche technique
Fiche technique
GRID2 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956153
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN1503169
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Competition ELISA
Validations
N° du produit
ABIN1503171
Quantité
96 tests
Fiche technique
Fiche technique
GRID2 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1355734
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3081263
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN3081264
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits GRID2
: "Differential localization of delta glutamate receptors in the rat cerebellum: coexpression with AMPA receptors in parallel fiber-spine synapses and absence from climbing fiber-spine synapses." dans: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 17, Issue 2, pp. 834-42, (1997) (PubMed).: "Neurodegeneration in Lurcher mice caused by mutation in delta2 glutamate receptor gene." dans: Nature, Vol. 388, Issue 6644, pp. 769-73, (1997) (PubMed).
: "Suppression of LTD in cultured Purkinje cells deficient in the glutamate receptor delta 2 subunit." dans: Neuroreport, Vol. 6, Issue 3, pp. 524-6, (1995) (PubMed).
: "Impairment of motor coordination, Purkinje cell synapse formation, and cerebellar long-term depression in GluR delta 2 mutant mice." dans: Cell, Vol. 81, Issue 2, pp. 245-52, (1995) (PubMed).
: "Selective expression of the glutamate receptor channel delta 2 subunit in cerebellar Purkinje cells." dans: Biochemical and biophysical research communications, Vol. 197, Issue 3, pp. 1267-76, (1994) (PubMed).
Synonymes et noms alternatifs relatifs à GRID2
glutamate receptor, ionotropic, delta 2 (grid2), glutamate receptor ionotropic, delta-2 (LOC704787), glutamate ionotropic receptor delta type subunit 2 (GRID2), glutamate receptor, ionotropic, delta 2 (Grid2), glutamate ionotropic receptor delta type subunit 2 (Grid2), glutamate receptor ionotropic, delta-2 (LOC536367), B230104L07Rik, cpr, GluD2, glurd2, GluRdelta2, GRID2, ho, Lc, LcProtein level used designations for GRID2
- gluR delta-2 subunit
- glutamate receptor delta-2 subunit
- glutamate receptor ionotropic, delta-2
- glutamate receptor, ionotropic, delta 2
- glutamate receptor delta-2 subunit-like
- GluR-delta-2
- creeper
- hotfoot
- lurcher
- minisatellite 10ac detected by probe MMS10
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