GSTA1 Produits
(Glutathione S-Transferase alpha 1 (GSTA1))
Catégories
Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008].
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Catégories GSTA1 en vedette
GSTA1 Anticorps
High quality antibodies with extensive validation data.
GSTA1 Kits ELISA
Reliable ELISA kits for a wide range of species.
GSTA1 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
GSTA1 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (6)
N° du produit
ABIN7234519
Quantité
200 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7432181
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC (p)
Validations
- (2)
- (4)
N° du produit
ABIN561158
Quantité
100 μg
Fiche technique
Fiche technique
GSTA1 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
N° du produit
ABIN6574174
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
N° du produit
ABIN6956213
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6967112
Quantité
96 tests
Fiche technique
Fiche technique
GSTA1 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7123136
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1306059
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Rat
Source
Escherichia coli (E. coli)
Validations
N° du produit
ABIN7505545
Quantité
100 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits GSTA1
: "Overexpression of Brg1 Alleviates Hepatic Ischemia/Reperfusion-Induced Acute Lung Injury through Antioxidative Stress Effects." dans: Oxidative medicine and cellular longevity, Vol. 2017, pp. 8787392, (2018) (PubMed).: "Oviductal Transcriptome Is Modified after Insemination during Spontaneous Ovulation in the Sow." dans: PLoS ONE, Vol. 10, Issue 6, pp. e0130128, (2015) (PubMed).
: "Comprehensive and temporal analysis of secreted proteins in the medium from IL-6 exposed human hepatocyte." dans: Biomedical chromatography : BMC, Vol. 28, Issue 6, pp. 742-50, (2014) (PubMed).
: "Redox protein expression predicts radiotherapeutic response in early-stage invasive breast cancer patients." dans: International journal of radiation oncology, biology, physics, Vol. 79, Issue 5, pp. 1532-40, (2011) (PubMed).
: "Early markers of tubular dysfunction in antiretroviral-experienced HIV-infected patients treated with tenofovir versus abacavir." dans: AIDS patient care and STDs, Vol. 26, Issue 1, pp. 5-11, (2011) (PubMed).
: "Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy." dans: Analytical cellular pathology (Amsterdam), Vol. 34, Issue 3, pp. 131-45, (2011) (PubMed).
: "Overcoming glutathione S-transferase P1-related cisplatin resistance in osteosarcoma." dans: Cancer research, Vol. 68, Issue 16, pp. 6661-8, (2008) (PubMed).
: "Caspases: the executioners of apoptosis." dans: The Biochemical journal, Vol. 326 ( Pt 1), Issue 5693, pp. 1-16, (1997) (PubMed).
: "Mch2, a new member of the apoptotic Ced-3/Ice cysteine protease gene family." dans: Cancer research, Vol. 55, Issue 13, pp. 2737-42, (1995) (PubMed).
Synonymes et noms alternatifs relatifs à GSTA1
glutathione S-transferase alpha 1 (GSTA1), glutathione S-transferase, alpha 1 (Ya) (Gsta1), glutathione S-transferase alpha 3 (GSTA3), glutathione S-transferase alpha 5 (GSTA5), glutathione S-transferase alpha 1 L homeolog (gsta1.L), glutathione S-transferase alpha 1 (gsta1), glutathione S-transferase alpha 2 (Gsta2), glutathione S-transferase mu 2 (muscle) (GSTM2), Glutathione S-transferase 2 (gst-2), glutathione S-transferase A (LOC100713029), glutathione S-transferase Gst2 (gst2), glutathione S-transferase 2 (LOC101897277), GST, Gst-2, Gst-3, GST2, gst2, Gst2, Gst2-1, Gst3, GSTA1, Gsta1, GSTA1-1, gsta1-1, GSTA3, GTH1, gth1, OTTMUSG00000031890Protein level used designations for GSTA1
- GST HA subunit 1
- GST class-alpha member 1
- GST, class alpha, 1
- GST-epsilon
- S-(hydroxyalkyl)glutathione lyase A1
- glutathione S-alkyltransferase A1
- glutathione S-aryltransferase A1
- glutathione S-transferase 2
- glutathione S-transferase A1
- glutathione S-transferase Ha subunit 1
- glutathione S-transferase Ya
- glutathione S-transferase Ya1
- glutathione S-transferase alpha 3
- glutathione S-transferase alpha 1
- glutathione S-transferase alpha-1
- GST class-alpha
- glutathione S-transferase alpha M14
- GST 1-1
- GST 1a-1a
- GST A1-1
- GST B
- GST Ya1
- Glutathione-S-transferase alpha type (Yc?)
- glutathione S-transferase A2
- glutathione S-transferase Ya subunit
- glutathione S-transferase Ya-1
- glutathione-S-transferase, alpha type2
- ligandin
- GST class-mu
- GST-CL2
- GSTM1-1
- glutathione S-transferases CL2
- GST-II
- GST class-theta
- Glutathione S-transferase 3
- glutatione transferase-2
- glutatione transferase-3C
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