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GSTM3 Produits

(Glutathione S-Transferase mu 3 (Brain) (GSTM3))

Catégories

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Mutations of this class mu gene have been linked with a slight increase in a number of cancers, likely due to exposure with environmental toxins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008].

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Catégories GSTM3 en vedette

GSTM3 Anticorps

High quality antibodies with extensive validation data.

GSTM3 Kits ELISA

Reliable ELISA kits for a wide range of species.

GSTM3 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GSTM3 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (8)
N° du produit ABIN5693252
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (p)
Validations
  • (7)
N° du produit ABIN5708464
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (3)
N° du produit ABIN7154107
Quantité 100 μg
Fiche technique Fiche technique

GSTM3 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6956224
Quantité 96 tests
Fiche technique Fiche technique

GSTM3 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7123142
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306082
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7405630
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GSTM3

Singh, Prasad, Singh, Singh, Gupta, Paliwal, Pandey, Gupta: "Human Glutathione S-Transferase Enzyme Gene Polymorphisms and Their Association With Neurocysticercosis." dans: Molecular neurobiology, (2016) (PubMed).

Venkataraman, den Braver, Vermeulen, Commandeur: "Cytochrome P450-mediated bioactivation of mefenamic acid to quinoneimine intermediates and inactivation by human glutathione S-transferases." dans: Chemical research in toxicology, Vol. 27, Issue 12, pp. 2071-81, (2014) (PubMed).

Hong, Heun, Jessen, Popp, Hentschel, Kelemen, Schulz, Maier, Kölsch: "Gene variations in GSTM3 are a risk factor for Alzheimer's disease." dans: Neurobiology of aging, Vol. 30, Issue 5, pp. 691-6, (2009) (PubMed).

Synonymes et noms alternatifs relatifs à GSTM3

glutathione S-transferase mu 3 (GSTM3), glutathione S-transferase Mu 3 (GSTM3), glutathione S-transferase, mu 3 (Gstm3), glutathione S-transferase Mu 3 (LOC479911), glutathione S-transferase mu 3 (Gstm3), Fsc2, GST5, GSTB, GSTM3-3, GTM3, mGSTM5

Protein level used designations for GSTM3

  • GST class-mu 3
  • S-(hydroxyalkyl)glutathione lyase M3
  • brain GST
  • brain type mu-glutathione S-transferase
  • glutathione S-alkyltransferase M3
  • glutathione S-aralkyltransferase M3
  • glutathione S-aryltransferase M3
  • glutathione S-transferase M3 (brain)
  • glutathione S-transferase Mu 3
  • glutathione S-transferase, Mu-3
  • hGSTM3-3
  • glutathione S-transferase M3
  • glutathione S-transferase GT9.3
  • glutathione S-transferase mu 3
  • glutathione-S-transferase, mu
  • glutathione S-transferase Mu 3-like
  • glutathione S-transferase Mu 5
  • GST class-mu 5
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