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GSTM4 Produits

(Glutathione S-Transferase mu 4 (GSTM4))

Catégories

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified. [provided by RefSeq, Jul 2008].

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Catégories GSTM4 en vedette

GSTM4 Anticorps

High quality antibodies with extensive validation data.

GSTM4 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

GSTM4 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (11)
N° du produit ABIN7439909
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (10)
N° du produit ABIN7444301
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application IHC, IF, FACS, StM
Validations
  • (5)
N° du produit ABIN6939574
Quantité 100 μg
Fiche technique Fiche technique

GSTM4 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6229643
Quantité 96 tests
Fiche technique Fiche technique

GSTM4 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN667165
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306087
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306085
Quantité 10 μg
Fiche technique Fiche technique

Dernières publications sur nos produits GSTM4

Ducy: "Bone Regulation of Insulin Secretion and Glucose Homeostasis." dans: Endocrinology, Vol. 161, Issue 10, (2020) (PubMed).

Denson, Xi, Wu, Yang, Neale, Zhang: "Screening for inter-individual splicing differences in human GSTM4 and the discovery of a single nucleotide substitution related to the tandem skipping of two exons." dans: Gene, Vol. 379, pp. 148-55, (2006) (PubMed).

Comstock, Johnson, Rifenbery, Henner: "Isolation and analysis of the gene and cDNA for a human Mu class glutathione S-transferase, GSTM4." dans: The Journal of biological chemistry, Vol. 268, Issue 23, pp. 16958-65, (1993) (PubMed).

Zhong, Spurr, Hayes, Wolf: "Deduced amino acid sequence, gene structure and chromosomal location of a novel human class Mu glutathione S-transferase, GSTM4." dans: The Biochemical journal, Vol. 291 ( Pt 1), pp. 41-50, (1993) (PubMed).

Ross, Board: "Molecular cloning and heterologous expression of an alternatively spliced human Mu class glutathione S-transferase transcript." dans: The Biochemical journal, Vol. 294 ( Pt 2), pp. 373-80, (1993) (PubMed).

Synonymes et noms alternatifs relatifs à GSTM4

glutathione S-transferase mu 4 (GSTM4), glutathione S-transferase mu 4 (Gstm4), glutathione S-transferase, mu 4 (Gstm4), 1110004G14Rik, Gstb-4, Gstb4, GSTM4-4, GSTM7-7, GTM4

Protein level used designations for GSTM4

  • glutathione S-transferase M4
  • GST class-mu 4
  • GST-Mu2
  • GTS-Mu2
  • S-(hydroxyalkyl)glutathione lyase M4
  • glutathione S-alkyltransferase M4
  • glutathione S-aralkyltransferase M4
  • glutathione S-aryltransferase M4
  • glutathione S-transferase Mu 4
  • glutathione S-transferase mu 3
  • glutathione S-transferase mu 4
  • glutathione-S-transferase, mu 4
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