HDAC4 Produits
(Histone Deacetylase 4 (HDAC4))
Catégories
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].
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Catégories HDAC4 en vedette
HDAC4 Anticorps
High quality antibodies with extensive validation data.
HDAC4 Kits ELISA
Reliable ELISA kits for a wide range of species.
HDAC4 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
HDAC4 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (5)
N° du produit
ABIN7441235
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IHC, ICC, FACS
Validations
- (5)
N° du produit
ABIN5542325
Quantité
0.1 mg
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, IF, IHC (p)
Validations
- (5)
N° du produit
ABIN523212
Quantité
100 μg
Fiche technique
Fiche technique
HDAC4 recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956574
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6956575
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
N° du produit
ABIN1380595
Quantité
2 x 96 tests
Fiche technique
Fiche technique
HDAC4 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
N° du produit
ABIN1306452
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1306454
Quantité
10 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3092909
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits HDAC4
: "Sarcoplasmic reticulum Ca2+ -induced Ca2+ release regulates class IIa HDAC localization in mouse embryonic cardiomyocytes." dans: Physiological reports, Vol. 6, Issue 2, (2019) (PubMed).: "Epigenetic effects of chromatin remodeling agents on organotypic cultures." dans: Epigenomics, Vol. 8, Issue 3, pp. 341-58, (2016) (PubMed).
: "HDAC4: a key factor underlying brain developmental alterations in CDKL5 disorder." dans: Human molecular genetics, Vol. 25, Issue 18, pp. 3887-3907, (2016) (PubMed).
: "Both HDAC5 and HDAC6 are required for the proliferation and metastasis of melanoma cells." dans: Journal of translational medicine, Vol. 14, pp. 7, (2016) (PubMed).
: "PARP-1 mediates LPS-induced HMGB1 release by macrophages through regulation of HMGB1 acetylation." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 12, pp. 6114-23, (2014) (PubMed).
: "Tasquinimod Is an Allosteric Modulator of HDAC4 survival signaling within the compromised cancer microenvironment." dans: Cancer research, Vol. 73, Issue 4, pp. 1386-99, (2013) (PubMed).
: "The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity." dans: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 34181-9, (2013) (PubMed).
: "Proteomics analysis of human obesity reveals the epigenetic factor HDAC4 as a potential target for obesity." dans: PLoS ONE, Vol. 8, Issue 9, pp. e75342, (2013) (PubMed).
: "HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration." dans: PLoS biology, Vol. 11, Issue 11, pp. e1001717, (2013) (PubMed).
: "Differential expression of mature microRNAs involved in muscle maintenance of hibernating little brown bats, Myotis lucifugus: a model of muscle atrophy resistance." dans: Genomics, proteomics & bioinformatics, Vol. 10, Issue 5, pp. 295-301, (2012) (PubMed).
Synonymes et noms alternatifs relatifs à HDAC4
histone deacetylase 4 (PTRG_03699), hypothetical protein (PGTG_15512), Histone deacetylase 4 (HDAC4), GF18710 gene product from transcript GF18710-RC (Dana\GF18710), histone deacetylase 4 (HDAC4), histone deacetylase 4 (Hdac4), histone deacetylase 4 (hdac4), 4932408F19Rik, AHO3, AI047285, BDMR, CG1770, DanaGF18710, dana_GLEANR_19966, DHDAC4, dHDAC4, Dmel\\CG1770, dmHDA405, GC1770, GF18710, HA6116, HD4, HDAC, HDAC-4, HDAC-A, hdac4, HDAC4, HDAC4a, HDACA, wu:fa96d08, wu:fc56f08, zgc:152701Protein level used designations for HDAC4
- histone deacetylase 4
- CG1770-PB
- CG1770-PD
- CG1770-PE
- CG1770-PF
- CG1770-PG
- CG1770-PH
- CG1770-PI
- CG1770-PJ
- HDAC4-PB
- HDAC4-PD
- HDAC4-PE
- HDAC4-PF
- HDAC4-PG
- HDAC4-PH
- HDAC4-PI
- HDAC4-PJ
- DanaGF18710-PA
- DanaHDAC4-PA
- GF18710-PA
- HDAC4
- HDAC4-PA
- histone deacetylase A
- HD4
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