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HDAC4/HDAC5/HDAC9 Anticorps

(HDAC4,HDAC5,HDAC9)
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

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HDAC4/HDAC5/HDAC9 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF, ELISA
Validations
  • (3)
N° du produit ABIN7138137
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, ELISA
Validations
  • (3)
N° du produit ABIN7138509
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, IF, IHC (p)
Validations
  • (3)
N° du produit ABIN319389
Quantité 0.1 mL
Fiche technique Fiche technique

Dernières publications sur nos produits HDAC4/HDAC5/HDAC9

Liu, Greer, Secombe: "KDM5 interacts with Foxo to modulate cellular levels of oxidative stress." dans: PLoS genetics, Vol. 10, Issue 10, pp. e1004676, (2014) (PubMed).

Vigushin, Coombes: "Targeted histone deacetylase inhibition for cancer therapy." dans: Current cancer drug targets, Vol. 4, Issue 2, pp. 205-18, (2004) (PubMed).

Thiagalingam, Cheng, Lee, Mineva, Thiagalingam, Ponte: "Histone deacetylases: unique players in shaping the epigenetic histone code." dans: Annals of the New York Academy of Sciences, Vol. 983, pp. 84-100, (2003) (PubMed).

Marmorstein: "Structure and function of histone acetyltransferases." dans: Cellular and molecular life sciences : CMLS, Vol. 58, Issue 5-6, pp. 693-703, (2001) (PubMed).

Synonymes et noms alternatifs relatifs à HDAC4/HDAC5/HDAC9

histone deacetylase 4 (HDAC4), AHO3, BDMR, HA6116, HD4, HDAC-4, HDAC-A, HDACA

Protein level used designations for HDAC4/HDAC5/HDAC9

  • histone deacetylase A
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