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HDAC5 Produits

(Histone Deacetylase 5 (HDAC5))
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the class II histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. It coimmunoprecipitates only with HDAC3 family member and might form multicomplex proteins. It also interacts with myocyte enhancer factor-2 (MEF2) proteins, resulting in repression of MEF2-dependent genes. This gene is thought to be associated with colon cancer. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Catégories HDAC5 en vedette

HDAC5 Anticorps

High quality antibodies with extensive validation data.

HDAC5 Kits ELISA

Reliable ELISA kits for a wide range of species.

HDAC5 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HDAC5 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN6141675
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (5)
N° du produit ABIN6262182
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (1)
  • (4)
N° du produit ABIN6255378
Quantité 100 μL
Fiche technique Fiche technique

HDAC5 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
N° du produit ABIN6956576
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN5691905
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380178
Quantité 2 x 96 tests
Fiche technique Fiche technique

HDAC5 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306456
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3092932
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3137643
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits HDAC5

Sarode, Neier, Shibata, Shen, Goncharov, Goncharova, Mazi, Joshi, Settles, LaSalle, Medici: "Wilson Disease: Intersecting DNA Methylation and Histone Acetylation Regulation of Gene Expression in a Mouse Model of Hepatic Copper Accumulation." dans: Cellular and molecular gastroenterology and hepatology, Vol. 12, Issue 4, pp. 1457-1477, (2022) (PubMed).

Feng, Zhong, Fan, Li, Shi, Jiang: "Upregulated Expression of Intestinal Antimicrobial Peptide HD5 Associated with Renal Function in IgA Nephropathy." dans: Disease markers, Vol. 2020, pp. 2078279, (2020) (PubMed).

Gupta, Jackson, DaJusta, McLeod, Alpert, Jayanthi, McHugh, Schwaderer, Becknell, Ching: "Urinary antimicrobial peptides: Potential novel biomarkers of obstructive uropathy." dans: Journal of pediatric urology, Vol. 14, Issue 3, pp. 238.e1-238.e6, (2018) (PubMed).

Watson, Hains, Cohen, Spencer, Kline, Yin, Schwaderer: "Evaluation of novel urinary tract infection biomarkers in children." dans: Pediatric research, Vol. 79, Issue 6, pp. 934-9, (2016) (PubMed).

Baek, Park, Rhim, Park, Kim, Kim, Nam: "Immunohistochemical Characterization of Histone Deacetylase as a Potential Prognostic Marker and Therapeutic Target in Endometrial Stromal Sarcoma." dans: Anticancer research, Vol. 36, Issue 5, pp. 2527-34, (2016) (PubMed).

Ow, Palanichamy Kala, Rao, Choi, Bharathy, Taneja: "G9a inhibits MEF2C activity to control sarcomere assembly." dans: Scientific reports, Vol. 6, pp. 34163, (2016) (PubMed).

Chen, Yin, Lao, Liang, He, Wang, Sang: "AMPK-HDAC5 pathway facilitates nuclear accumulation of HIF-1α and functional activation of HIF-1 by deacetylating Hsp70 in the cytosol." dans: Cell cycle (Georgetown, Tex.), Vol. 14, Issue 15, pp. 2520-36, (2015) (PubMed).

Alam, Rashid, Kabir, Raqib, Ahmad: "On birth single dose live attenuated OPV and BCG vaccination induces gut cathelicidin LL37 responses at 6 week of age: a natural experiment." dans: Vaccine, Vol. 33, Issue 1, pp. 18-21, (2014) (PubMed).

Cao, Li, Zhu, Shen, Han, Zhang, Yu, Wang, Wu, Chen, Sun, Tang, Zhao, Qiao, Hou, Mao: "The antiparasitic clioquinol induces apoptosis in leukemia and myeloma cells by inhibiting histone deacetylase activity." dans: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 34181-9, (2013) (PubMed).

Yamaguchi, Chakraborty, Pasek, Molkentin, Meissner: "Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules." dans: American journal of physiology. Heart and circulatory physiology, Vol. 300, Issue 6, pp. H2187-95, (2011) (PubMed).

Synonymes et noms alternatifs relatifs à HDAC5

histone deacetylase 5 (HDAC5), histone deacetylase 5 (Hdac5), histone deacetylase 5 (HDA05), histone deacetylase 5 (hdac5), AI426555, ATHDA5, HD5, HDA5, Hdac4, histone deacetylase 5, MAF19.7, MAF19_7, mHDA1, mKIAA0600, NY-CO-9

Protein level used designations for HDAC5

  • antigen NY-CO-9
  • HD5
  • histone deacetylase 4
  • histone deacetylase mHDA1
  • histone deacetylase 5
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