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HEY2 Produits

(Hairy/enhancer-of-Split Related with YRPW Motif 2 (HEY2))

Catégories

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].

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Catégories HEY2 en vedette

HEY2 Anticorps

High quality antibodies with extensive validation data.

HEY2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

HEY2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse
Application WB, IHC (p)
Validations
  • (3)
N° du produit ABIN652095
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA
Validations
  • (3)
N° du produit ABIN949119
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Zebrafish (Danio rerio)
Application WB
Validations
  • (3)
  • (1)
N° du produit ABIN1881411
Quantité 400 μL
Fiche technique Fiche technique

HEY2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306572
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1306574
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3081431
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits HEY2

Tang, Urs, Liaw: "Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site." dans: Circulation research, Vol. 102, Issue 6, pp. 661-8, (2008) (PubMed).

Winkler, Elmasri, Klamt, Volff, Gessler: "Characterization of hey bHLH genes in teleost fish." dans: Development genes and evolution, Vol. 213, Issue 11, pp. 541-53, (2003) (PubMed).

Zhong, Childs, Leu, Fishman: "Gridlock signalling pathway fashions the first embryonic artery." dans: Nature, Vol. 414, Issue 6860, pp. 216-20, (2001) (PubMed).

Zhong, Rosenberg, Mohideen, Weinstein, Fishman: "gridlock, an HLH gene required for assembly of the aorta in zebrafish." dans: Science (New York, N.Y.), Vol. 287, Issue 5459, pp. 1820-4, (2000) (PubMed).

Synonymes et noms alternatifs relatifs à HEY2

hes related family bHLH transcription factor with YRPW motif 2 (HEY2), hairy/enhancer-of-split related with YRPW motif 2 (Hey2), hes-related family bHLH transcription factor with YRPW motif 2 (hey2), hes-related family bHLH transcription factor with YRPW motif 2 (Hey2), bHLHb32, CHF1, GRIDLOCK, GRL, grl, HERP1, Herp1, HESR2, hesr2, HRT2, Hrt2, zgc:136746

Protein level used designations for HEY2

  • hairy/enhancer-of-split related with YRPW motif protein 2
  • HES-related repressor protein 1
  • HES-related repressor protein 2
  • HESR-2
  • HRT-2
  • cardiovascular basic helix-loop-helix factor 1
  • cardiovascular helix-loop-helix factor 1
  • class B basic helix-loop-helix protein 32
  • hCHF1
  • hHRT2
  • hairy and enhancer of split-related protein 2
  • hairy-related transcription factor 2
  • protein gridlock homolog
  • Hairy-E(spl)-related with YRPW motif 2
  • hairy and enhancer of split related 2
  • mHRT2
  • Herp2
  • gridlock
  • protein gridlock
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